CD180 Rabbit Polyclonal Antibody — image 1 of 3

Product details

CD180 Rabbit Polyclonal Antibody

Catalog number ER2001-06

Price for ER2001-06

Size / count 100 µL

About this product

CD180 antigen is a protein that in humans is encoded by the CD180 gene. CD180 is a cell surface molecule consisting of extracellular leucine-rich repeats (LRR) and a short cytoplasmic tail. It is also known by the archaic terms Bgp-95 and RP105, for the founding designations following discovery in humans (1988) and mice (1994), respectively. CD180 is expressed on antigen presenting cells including B cells and dendritic cells. The extracellular LRR is associated with a molecule called MD-1 and form the cell surface receptor complex, CD180/MD-1. It belongs to the family of pathogen receptors, Toll-like receptors (TLR). CD180/MD-1, by working in concert with TLR4, controls B cell recognition and signaling of lipopolysaccharide (LPS), a membrane constituent of Gram-negative bacteria. Recently, CD180 has been demonstrated to be involved in the survival and prognosis of B-cell chronic lymphocytic leukemia.

Specifications

Catalog number: ER2001-06
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CD180 antibody CD180 antigen antibody CD180_HUMAN antibody F630107B15 antibody LY64 antibody Ly78 antibody Lymphocyte antigen 64 antibody lymphocyte antigen 64 radioprotective 105kDa antibody lymphocyte antigen-64, radioprotective, 105kDa antibody MGC126233 antibody MGC126234 antibody Radioprotective 105 kDa protein antibody RP105 antibody
Abbreviation: CD180
Swiss Prot: Q99467 Human, Q62192 Mouse
Cellular Locus: Cell membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human CD180 aa 370-580.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: Daudi cell lysate, rat spleen tissue lysate, mouse spleen tissue lysate, rat spleen tissue, human spleen tissue, mouse spleen tissue, Daudi.
Concentration: 1 mg/mL
Dilution: WB:1:500-1:2,000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 74 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for CD180 Rabbit Polyclonal Antibody?

The catalog number for CD180 Rabbit Polyclonal Antibody is ER2001-06.

What sizes are available for CD180 Rabbit Polyclonal Antibody?

CD180 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is CD180 Rabbit Polyclonal Antibody in stock?

CD180 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD180 Rabbit Polyclonal Antibody used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.