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Product details

CD35 Rabbit Polyclonal Antibody

Catalog number ER2001-14

Price for ER2001-14

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Size / count 100 µL

About this product

Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages . Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the circulation . Acts also in the inhibition of spontaneous complement activation by impairing the formation and function of the alternative and classical pathway C3/C5 convertases, and by serving as a cofactor for the cleavage by factor I of C3b to iC3b, C3c and C3d,g, and of C4b to C4c and C4d. Plays also a role in immune regulation by contributing, upon ligand binding, to the generation of regulatory T cells from activated helper T cells .

Specifications

Catalog number
ER2001-14
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
C3 binding protein antibody C3b/C4b receptor antibody C3BR antibody C4BR antibody CD 35 antibody CD35 antibody CD35 antigen antibody complement component (3b/4b) receptor 1 (Knops blood group) antibody complement component (3b/4b) receptor 1 including Knops blood group system antibody Complement component receptor 1 antibody Complement receptor 1 antibody Complement receptor type 1 antibody CR 1 antibody CR1 antibody CR1_HUMAN antibody KN antibody Knops blood group antigen antibody
Abbreviation
Complement receptor type 1 CR1 C3b/C4b receptor CD35
Swiss Prot
P17927 Human
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within human Complement receptor type 1 aa 600-800.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
HL-60 cell lysates, recombinant protein lysates, human spleen tissue, human kidney tissue, Daudi.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:50-1:200 ;FC: 1;50-1:100
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 224 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for CD35 Rabbit Polyclonal Antibody?

The catalog number for CD35 Rabbit Polyclonal Antibody is ER2001-14.

What sizes are available for CD35 Rabbit Polyclonal Antibody?

CD35 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is CD35 Rabbit Polyclonal Antibody in stock?

CD35 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD35 Rabbit Polyclonal Antibody used for?

Membrane immune adherence receptor that plays a critical role in the capture and clearance of complement-opsonized pathogens by erythrocytes and monocytes/macrophages . Mediates the binding by these cells of particles and immune complexes that have activated complement to eliminate them from the cir

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

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