Flt3 Rabbit Polyclonal Antibody — image 1 of 3

Product details

Flt3 Rabbit Polyclonal Antibody

Catalog number ER2001-25

Price for ER2001-25

Size / count 100 µL

About this product

Tyrosine-protein kinase that acts as cell-surface receptor for the cytokine FLT3LG and regulates differentiation, proliferation and survival of hematopoietic progenitor cells and of dendritic cells. Promotes phosphorylation of SHC1 and AKT1, and activation of the downstream effector MTOR. Promotes activation of RAS signaling and phosphorylation of downstream kinases, including MAPK1/ERK2 and/or MAPK3/ERK1. Promotes phosphorylation of FES, FER, PTPN6/SHP, PTPN11/SHP-2, PLCG1, and STAT5A and/or STAT5B. Activation of wild-type FLT3 causes only marginal activation of STAT5A or STAT5B. Mutations that cause constitutive kinase activity promote cell proliferation and resistance to apoptosis via the activation of multiple signaling pathways.

Specifications

Catalog number: ER2001-25
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CD 135 antibody CD135 antibody CD135 antigen antibody Fetal liver kinase 2 antibody FL cytokine receptor antibody Flk 2 antibody Flk2 antibody Flt 3 antibody FLT-3 antibody Flt3 antibody FLT3_HUMAN antibody FMS like tyrosine kinase 3 antibody Fms related tyrosine kinase 3 antibody Fms-like tyrosine kinase 3 antibody Growth factor receptor tyrosine kinase type III antibody Ly-72 antibody OTTHUMP0000004234 antibody Receptor type tyrosine protein kinase FLT3 antibody Stem cell tyrosine kinase 1 antibody Stk 1 antibody STK-1 antibody Stk1 antibody Tyrosine protein kinase receptor FLT3 antibody Tyrosine-protein kinase receptor FLT3 antibody
Abbreviation: FLT3
Swiss Prot: P36888 Human, Q00342 Mouse
Cellular Locus: Endoplasmic reticulum lumen, membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within mouse Flt3 aa 30-80.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, FC, IF-Cell
Positive Control: Rat testis lysates, 293T, rat testis tissue, human liver tissue, human spleen tissue, human placenta tissue, mouse brain tissue, THP-1.
Concentration: 1 mg/mL
Dilution: WB:1:500-1:2,000 ;IHC-P:1:50-1:200 ;FC:1:50-1:100 ;IF-Cell:1:50
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 1%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 113 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Flt3 Rabbit Polyclonal Antibody?

The catalog number for Flt3 Rabbit Polyclonal Antibody is ER2001-25.

What sizes are available for Flt3 Rabbit Polyclonal Antibody?

Flt3 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Flt3 Rabbit Polyclonal Antibody in stock?

Flt3 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Flt3 Rabbit Polyclonal Antibody used for?

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.