AKR1B1 Rabbit Polyclonal Antibody — image 1 of 3

Product details

AKR1B1 Rabbit Polyclonal Antibody

Catalog number ER2001-27

Price for ER2001-27

Size / count 100 µL

About this product

Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols. Displays enzymatic activity towards endogenous metabolites such as aromatic and aliphatic aldehydes, ketones, monosacharides, bile acids and xenobiotics substrates. Key enzyme in the polyol pathway, catalyzes reduction of glucose to sorbitol during hyperglycemia . Reduces steroids and their derivatives and prostaglandins. Displays low enzymatic activity toward all-trans-retinal, 9-cis-retinal, and 13-cis-retinal . Catalyzes the reduction of diverse phospholipid aldehydes such as 1-palmitoyl-2- (5-oxovaleroyl)-sn -glycero-3-phosphoethanolamin (POVPC) and related phospholipid aldehydes that are generated from the oxydation of phosphotidylcholine and phosphatdyleethanolamides. Plays a role in detoxifying dietary and lipid-derived unsaturated carbonyls, such as crotonaldehyde, 4-hydroxynonenal, trans-2-hexenal, trans-2,4-hexadienal and their glutathione-conjugates carbonyls (GS-carbonyls) .

Specifications

Catalog number: ER2001-27
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: ADR antibody AKR1B 1 antibody Akr1b1 antibody Aldehyde reductase 1 antibody Aldehyde reductase antibody Aldo keto reductase family 1, member B1 antibody Aldo-keto reductase family 1 member B1 antibody aldo-keto reductase family 1, member B1 (aldose reductase) antibody Aldose reductase antibody aldr 1 antibody ALDR_HUMAN antibody aldr1 antibody ALR2 antibody AR antibody Lii5 2 CTCL tumor antigen antibody Low Km aldose reductase antibody MGC1804 antibody
Abbreviation: Aldo-keto reductase family 1 member B1 Aldehyde reductase Aldose reductase AR
Swiss Prot: P15121 Human
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Rat, Mouse
Immunogen: Synthetic peptide within human AKR1B1 aa 1-50.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: Rat skeletal muscle tissue lysate, A549 cell lysate, rat seminal vesicle tissue, human seminal vesicle tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IHC-P: 1:100-1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 36 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for AKR1B1 Rabbit Polyclonal Antibody?

The catalog number for AKR1B1 Rabbit Polyclonal Antibody is ER2001-27.

What sizes are available for AKR1B1 Rabbit Polyclonal Antibody?

AKR1B1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is AKR1B1 Rabbit Polyclonal Antibody in stock?

AKR1B1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is AKR1B1 Rabbit Polyclonal Antibody used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.