COPS8 Rabbit Polyclonal Antibody — image 1 of 3

Product details

COPS8 Rabbit Polyclonal Antibody

Catalog number ER2001-29

Price for ER2001-29

Size / count 100 µL

About this product

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1 and IRF8/ICSBP, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively.

Specifications

Catalog number: ER2001-29
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: COP9 homolog antibody COP9 signalosome complex subunit 8 antibody COP9 signalosome subunit 8 antibody Cops8 antibody CSN8 antibody CSN8_HUMAN antibody hCOP9 antibody JAB1 containing signalosome subunit 8 antibody JAB1-containing signalosome subunit 8 antibody SGN8 antibody Signalosome subunit 8 antibody
Abbreviation: COP9 signalosome complex subunit 8,SGN8,Signalosome subunit 8,COP9 homolog hCOP9 JAB1-containing signalosome subunit 8
Swiss Prot: Q99627 Human, Q8VBV7 Mouse, Q6P4Z9 Rat
Cellular Locus: Cytoplasm, Nucleus, Signalosome.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human COPS8 aa 1-300.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P
Positive Control: SHSY5Y cell lysate, HL-60 cell lysate, rat brain tissue, rat cerebellum tissue, human liver tissue, human liver carcinoma tissue, mouse brain tissue.
Concentration: 1 mg/mL
Dilution: WB:1:500-1:1,000;IHC-P: 1:100-1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 23 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for COPS8 Rabbit Polyclonal Antibody?

The catalog number for COPS8 Rabbit Polyclonal Antibody is ER2001-29.

What sizes are available for COPS8 Rabbit Polyclonal Antibody?

COPS8 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is COPS8 Rabbit Polyclonal Antibody in stock?

COPS8 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is COPS8 Rabbit Polyclonal Antibody used for?

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.