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Product details

CLIC1 Rabbit Polyclonal Antibody

Catalog number ER2001-32

Price for ER2001-32

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Size / count 100 µL

About this product

Chloride intracellular channel protein 1 is a protein that in humans is encoded by the CLIC1 gene. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle. Mainly cytoplasmic expression in most glandular epithelial cells, also membranous expression in renal tubules. CLIC1 is frequently upregulated in multiple human malignancies and has been demonstrated to play a critical role in cell proliferation, apoptosis, and invasion. However, limited is known about its expression, biological functions, and action mechanism in oral malignancies.

Specifications

Catalog number
ER2001-32
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Chloride channel ABP antibody Chloride intracellular channel 1 antibody Chloride intracellular channel protein 1 antibody CLIC 1 antibody CLIC1 antibody CLIC1_HUMAN antibody G6 antibody hRNCC antibody NCC 27 antibody NCC27 antibody Nuclear chloride ion channel 27 antibody Nuclear chloride ion channel protein antibody p64CLCP antibody Regulatory nuclear chloride ion channel protein antibody RNCC protein antibody
Abbreviation
NCC27, hRNCC, CLIC1, G6, NCC27
Swiss Prot
O00299 Human, Q9Z1Q5 Mouse, Q6MG61 Rat
Cellular Locus
Cell membrane, Cytoplasm, Membrane, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human CLIC1 aa 1-200.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P
Positive Control
Mouse kidney tissue lysates, A431, MG-63, SKOV-3, rat large intestine tissue, human kidney tissue, human placenta tissue, mouse colon tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000;IF-Cell: 1:50-1:200;IHC-P: 1:50-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 1% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
27 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for CLIC1 Rabbit Polyclonal Antibody?

The catalog number for CLIC1 Rabbit Polyclonal Antibody is ER2001-32.

What sizes are available for CLIC1 Rabbit Polyclonal Antibody?

CLIC1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is CLIC1 Rabbit Polyclonal Antibody in stock?

CLIC1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is CLIC1 Rabbit Polyclonal Antibody used for?

Chloride intracellular channel protein 1 is a protein that in humans is encoded by the CLIC1 gene. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellula

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

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