Product details
Catalog number ER2001-32
Price for ER2001-32
Size / count 100 µL
Chloride intracellular channel protein 1 is a protein that in humans is encoded by the CLIC1 gene. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 1 is a member of the p64 family; the protein localizes principally to the cell nucleus and exhibits both nuclear and plasma membrane chloride ion channel activity. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions. Involved in regulation of the cell cycle. Mainly cytoplasmic expression in most glandular epithelial cells, also membranous expression in renal tubules. CLIC1 is frequently upregulated in multiple human malignancies and has been demonstrated to play a critical role in cell proliferation, apoptosis, and invasion. However, limited is known about its expression, biological functions, and action mechanism in oral malignancies.
The catalog number for CLIC1 Rabbit Polyclonal Antibody is ER2001-32.
CLIC1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.
CLIC1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.
Chloride intracellular channel protein 1 is a protein that in humans is encoded by the CLIC1 gene. Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellula
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The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.
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