CD28 Rabbit Polyclonal Antibody — image 1 of 3

Product details

CD28 Rabbit Polyclonal Antibody

Catalog number ER2001-42

Price for ER2001-42

Size / count 100 µL

About this product

CD28 (Cluster of Differentiation 28) is one of the proteins expressed on T cells that provide co-stimulatory signals required for T cell activation and survival. T cell stimulation through CD28 in addition to the T-cell receptor (TCR) can provide a potent signal for the production of various interleukins (IL-6 in particular). CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2) proteins. When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen-presenting cells (APCs). The CD86 expression on antigen-presenting cells is constitutive (expression is independent of environmental factors). CD28 is the only B7 receptor constitutively expressed on naive T cells. Association of the TCR of a naive T cell with MHC:antigen complex without CD28:B7 interaction results in a T cell that is anergic.

Specifications

Catalog number: ER2001-42
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CD 28 antibody CD28 antibody CD28 antigen antibody CD28 molecule antibody CD28_HUMAN antibody MGC138290 antibody T cell antigen CD28 antibody T cell specific surface glycoprotein antibody T cell specific surface glycoprotein CD28 antibody T-cell-specific surfac
Abbreviation: TP44,T-cell-specific surface glycoprotein CD28
Swiss Prot: P10747 Human, P31041 Mouse, P31042 Rat
Cellular Locus: Membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human CD28 aa 170-220.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: Mouse spleen tissue lysate, U937 cell lysate, rat spleen tissue, human tonsils tissue, human spleen tissue, mouse spleen tissue, Jurkat.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000;IHC-P: 1:50-1:200;FC: 1:100-1:500
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 25 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for CD28 Rabbit Polyclonal Antibody?

The catalog number for CD28 Rabbit Polyclonal Antibody is ER2001-42.

What sizes are available for CD28 Rabbit Polyclonal Antibody?

CD28 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is CD28 Rabbit Polyclonal Antibody in stock?

CD28 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD28 Rabbit Polyclonal Antibody used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.