FCGRT Rabbit Polyclonal Antibody

Catalog number ER2001-44

Price for ER2001-44

Size / count 100 µL

About this product

Cell surface receptor that transfers passive humoral immunity from the mother to the newborn. Binds to the Fc region of monomeric immunoglobulin gamma and mediates its selective uptake from milk . IgG in the milk is bound at the apical surface of the intestinal epithelium. The resultant FcRn-IgG complexes are transcytosed across the intestinal epithelium and IgG is released from FcRn into blood or tissue fluids. Throughout life, contributes to effective humoral immunity by recycling IgG and extending its half-life in the circulation. Mechanistically, monomeric IgG binding to FcRn in acidic endosomes of endothelial and hematopoietic cells recycles IgG to the cell surface where it is released into the circulation . In addition of IgG, regulates homeostasis of the other most abundant circulating protein albumin/ALB .

Specifications

Catalog number: ER2001-44
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Alpha chain antibody Fc fragment of IgG, receptor transporter, alpha antibody FCGRN_HUMAN antibody FCGRT antibody FcRn alpha chain antibody FcRn antibody FCRN, alpha chain antibody IgG Fc fragment receptor transporter alpha chain antibody IgG Gc receptor antibody IgG receptor FcRn large subunit p51 antibody IgG receptor FcRn large subunit p51 precursor antibody Immunoglobulin receptor, intestinal, heavy chain antibody Neonatal Fc receptor antibody
Abbreviation: IgG receptor FcRn large subunit p51 FcRn IgG Fc fragment receptor transporter alpha chain Neonatal Fc receptor FCGRT
Swiss Prot: P55899 Human
Cellular Locus: Cell membrane, Endosome, Membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within human FCGRT aa 20-70.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB
Positive Control: Human brain tissue lysate, HepG2 cell lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 40 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for FCGRT Rabbit Polyclonal Antibody?

The catalog number for FCGRT Rabbit Polyclonal Antibody is ER2001-44.

What sizes are available for FCGRT Rabbit Polyclonal Antibody?

FCGRT Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is FCGRT Rabbit Polyclonal Antibody in stock?

FCGRT Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is FCGRT Rabbit Polyclonal Antibody used for?

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.