MGMT Rabbit Polyclonal Antibody — image 1 of 3

Product details

MGMT Rabbit Polyclonal Antibody

Catalog number ER40104

Price for ER40104

Size / count 100 µL

About this product

MGMT (O-6-methylguanine-DNA methyltransferase) is a DNA repair enzyme that participates in a suicide reaction that specifically removes methyl or alkyl groups from the O (6) position of guanine, restoring guanine to its normal form without causing DNA breaks. MGMT protects cells from alkylating toxins, and is an important factor in drug resistance to alkylating therapeutic agents. It is ubiquitously expressed in normal human tissues and is overexpressed in many types of human tumors, but epigenetically silenced in other tumors. MGMT silencing is a marker associated with poor prognosis, but is a good predictive marker for response to alkylating agent chemotherapy.

Specifications

Catalog number: ER40104
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 6 O methylguanine DNA methyltransferase antibody 6-O-methylguanine-DNA methyltransferase antibody Agat antibody AGT antibody AI267024 antibody EC 2.1.1.63 antibody Methylated DNA protein cysteine methyltransferase antibody Methylated-DNA--protein-cysteine methyltransferase antibody Methylguanine DNA methyltransferase antibody MGC107020 antibody MGMT antibody MGMT_HUMAN antibody O 6 methylguanine DNA alkyltransferase antibody O 6 methylguanine DNA methyltransferase antibody O-6-methylguanine-DNA methyltransferase antibody O-6-methylguanine-DNA-alkyltransferase antibody
Abbreviation: MGMT
Swiss Prot: P16455 Human
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within residues of MGMT aa 158-207 / 207.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: MCF-7 cell lysate, Hela cell lysate, Dauai cell lysate, Raji cell lysate, SK-BR-3 cell lysate, SKOV3 cell lysate, human kidney tissue lysate, human liver tissue lysate, human thymus tissue lysate, human placentae tissue lysate, A172, SK-BR-3, MCF-7, human tonsil tissue, human colon carcinoma tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000;IF-Cell: 1:200;IHC-P: 1:200;FC:1:100
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 22 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for MGMT Rabbit Polyclonal Antibody?

The catalog number for MGMT Rabbit Polyclonal Antibody is ER40104.

What sizes are available for MGMT Rabbit Polyclonal Antibody?

MGMT Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is MGMT Rabbit Polyclonal Antibody in stock?

MGMT Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is MGMT Rabbit Polyclonal Antibody used for?

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.