Desmin Rabbit Polyclonal Antibody — image 1 of 3

Product details

Desmin Rabbit Polyclonal Antibody

Catalog number ER40113

Price for ER40113

Size / count 100 µL

About this product

Desmin is one of the earliest protein markers for muscle tissue in embryogenesis as it is detected in the somites. Although it is present early in the development of muscle cells, it is only expressed at low levels, and increases as the cell nears terminal differentiation. Desmin is also important in muscle cell architecture and structure since it connects many components of the cytoplasm. Finally, desmin may be important in mitochondria function. Desmin-related myopathy (DRM or Desminopathy) is a subgroup of the myofibrillar myopathy diseases and is the result of a mutation in the gene that codes for desmin which prevents it from forming protein filaments, instead forming aggregates of desmin and other proteins throughout the cell. Recently, mutations were identified in patients suffered by an arrhythmogenic right ventricular cardiomyopathy (ARVC).

Specifications

Catalog number: ER40113
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CMD1I antibody CSM1 antibody CSM2 antibody DES antibody DESM_HUMAN antibody Desmin antibody FLJ12025 antibody FLJ39719 antibody FLJ41013 antibody FLJ41793 antibody Intermediate filament protein antibody OTTHUMP00000064865 antibody
Swiss Prot: P17661 Human
Cellular Locus: Cytoplasm, Cell membrane, Intermediate filament, Membrane, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Zebrafish
Immunogen: Recombinant protein within human Desmin aa 405-470/470.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: Human heart tissue lysate, human skeletal muscle tissue lysate, mouse heart tissue lysate, human uterus tissue, mouse skeletal muscle tissue, mouse heart tissue, hybrid fish (crucian-carp) brain tissue lysate, HepG2, NIH-3T3, Hela.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000;IF-Cell: 1:200;IHC-P: 1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 54 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for Desmin Rabbit Polyclonal Antibody?

The catalog number for Desmin Rabbit Polyclonal Antibody is ER40113.

What sizes are available for Desmin Rabbit Polyclonal Antibody?

Desmin Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Desmin Rabbit Polyclonal Antibody in stock?

Desmin Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Desmin Rabbit Polyclonal Antibody used for?

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.