ROCK1 Rabbit Polyclonal Antibody — image 1 of 2

Product details

ROCK1 Rabbit Polyclonal Antibody

Catalog number ER40122

Price for ER40122

Size / count 100 µL

About this product

ROCK1 is a protein serine/threonine kinase also known as rho-associated, coiled-coil-containing protein kinase 1. ROCK1 has a ubiquitous tissue distribution, but subcellularly it is thought to colocalize with the centrosomes. This is consistent with its function as a key modulator of cell motility, tumor cell invasion, and actin cytoskeleton organization. ROCK1 has a diverse range of functions in the body. It is a key regulator of actin-myosin contraction, stability, and cell polarity. These contribute to many progresses such as regulation of morphology, gene transcription, proliferation, differentiation, apoptosis and oncogenic transformation. Other functions involve smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility. These functions are activated by phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A.

Specifications

Catalog number: ER40122
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: coiled-coil-containing protein kinase 1 antibody coiled-coil-containing protein kinase I antibody MGC131603 antibody MGC43611 antibody p160 Rhoassociated coiled coil-forming protein kinase antibody p160 ROCK-1 antibody p160 ROCK1 antibody p160ROCK antibody PRO0435 antibody Renal carcinoma antigen NY REN 35 antibody Renal carcinoma antigen NY-REN-35 antibody Rho associated coiled coil containing protein kinase 1 antibody Rho associated protein kinase 1 antibody Rho kinase antibody Rho-alpha kinase antibody Rho-associated antibody Rho-associated protein kinase 1 antibody ROCK I antibody ROCK-I antibody ROCK1 antibody ROCK1_HUMAN antibody Rok antibody rokalpha antibody
Abbreviation: ROCK-I,p160ROCK
Swiss Prot: Q13464 Human, P70335 Mouse, Q63644 Rat
Cellular Locus: Cytoplasm, cell membrane, Nucleus, Cell projection, Cytoskeleton, Golgi apparatus, Membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within residues of ROCK1 aa 1,305-1,354 / 1,354.
Isotype: IgG
Conjugation: Non-conjugated
Type: Rabbit polyclonal Antibody
Applications: WB, IHC-P, IF-Cell, FC
Positive Control: A431 cell lysate, human lung tissue lysate, mouse spleen tissue lysate, C6 cell lysate, L6 cell lysate, human colon cancer tissue, HepG2.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IHC-P: 1:200 ;IF-Cell: 1:50 ;FC: 1:100-1:200
Purity: Immunogen affinity purified.
Form: Liquid
Buffer: 1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 158 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for ROCK1 Rabbit Polyclonal Antibody?

The catalog number for ROCK1 Rabbit Polyclonal Antibody is ER40122.

What sizes are available for ROCK1 Rabbit Polyclonal Antibody?

ROCK1 Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is ROCK1 Rabbit Polyclonal Antibody in stock?

ROCK1 Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is ROCK1 Rabbit Polyclonal Antibody used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.