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Product details

Topoisomerase II alpha Rabbit Polyclonal Antibody

Catalog number ER40124

Price for ER40124

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Size / count 100 µL

About this product

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and replication. It catalyzes the transient breaking and rejoining of two strands of duplex DNA which allows the strands to pass through one another, thus altering the topology of DNA. Two forms of this enzyme exist as likely products of a gene duplication event. It is essential during mitosis and meiosis for proper segregation of daughter chromosomes.

Specifications

Catalog number
ER40124
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
alpha isozyme antibody ATP hydrolyzing DNA topoisomerase II alfa antibody DNA gyrase antibody DNA topoisomerase (ATP hydrolyzing) antibody DNA topoisomerase 2 alpha antibody DNA topoisomerase 2-alpha antibody DNA topoisomerase II 170 kD antibody DNA topoisomerase II alpha isozyme antibody DNA topoisomerase II antibody DNA Topoisomerase2 antibody TOP 2A antibody TOP2 antibody TOP2A antibody TOP2A_HUMAN antibody Topoisomerase DNA II alpha 170kDa antibody TP2A antibody
Abbreviation
TOP2A
Swiss Prot
P11388 Human
Cellular Locus
Cytoplasm, nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within C-terminal residues of Topoisomerase II alpha.
Isotype
IgG
Conjugation
Non-conjugated
Type
Rabbit polyclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
Jurkat cell lysate, NIH/3T3 cell lysate, A431 cell lysate, L929 cell lysate, A549 cell lysate, Human liver tissue lysate, HUVEC cell lysate, A549, Hela, A431, NIH/3T3, human tonsil tissue, human colon cancer tissue, human colon cancer tissue, Hela.
Concentration
1 mg/mL
Dilution
WB: 1:500;IF-Cell: 1:200;IHC-P: 1:200;FC: 1:100-1:200
Purity
Immunogen affinity purified.
Form
Liquid
Buffer
1*PBS (pH7.4), 0.2% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 174 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Topoisomerase II alpha Rabbit Polyclonal Antibody?

The catalog number for Topoisomerase II alpha Rabbit Polyclonal Antibody is ER40124.

What sizes are available for Topoisomerase II alpha Rabbit Polyclonal Antibody?

Topoisomerase II alpha Rabbit Polyclonal Antibody is available in the following size(s): 100 µL.

Is Topoisomerase II alpha Rabbit Polyclonal Antibody in stock?

Topoisomerase II alpha Rabbit Polyclonal Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

What is Topoisomerase II alpha Rabbit Polyclonal Antibody used for?

This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This nuclear enzyme is involved in processes such as chromosome condensation, chromatid separation, and the relief of torsional stress that occurs during DNA transcription and

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

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