GFAP Recombinant Rabbit Monoclonal Antibody [SA03-04]

About this product

Glial fibrillary acidic protein (GFAP) is a protein that is encoded by the GFAP gene in humans. It is a type III intermediate filament (IF) protein that is expressed by numerous cell types of the central nervous system (CNS), including astrocytes and ependymal cells during development. GFAP has also been found to be expressed in glomeruli and peritubular fibroblasts taken from rat kidneys, Leydig cells of the testis in both hamsters and humans, human keratinocytes, human osteocytes and chondrocytes and stellate cells of the pancreas and liver in rats. GFAP is closely related to the other three non-epithelial type III IF family members, vimentin, desmin and peripherin, which are all involved in the structure and function of the cell’s cytoskeleton. GFAP is thought to help to maintain astrocyte mechanical strength as well as the shape of cells, but its exact function remains poorly understood, despite the number of studies using it as a cell marker.

Specifications

Catalog number

ET1601-23

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

wu:fb34h11 antibody ALXDRD antibody cb345 antibody etID36982.3 antibody FLJ42474 antibody FLJ45472 antibody GFAP antibody GFAP_HUMAN antibody gfapl antibody Glial fibrillary acidic protein antibody Intermediate filament protein antibody wu:fk42c12 antibody xx:af506734 antibody zgc:110485 antibody

Abbreviation

GFAP

Swiss Prot

P14136 Human, P03995 Mouse, P47819 Rat

Cellular Locus

Cytoplasm

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human GFAP aa 1-50 / 432.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Tissue, IHC-Fr, mIHC, IP

Positive Control

Human brain tissue lysate, rat brain tissue lysate, human cerebellum tissue lysate, mouse brain tissue, rat brain tissue, human brain tissue, human glioblastoma tissue, mouse spinal cord tissue, rat spinal cord tissue, mouse cerebral cortex tissue, rat cerebral cortex tissue, mouse cerebellum tissue, rat cerebellum tissue, mouse hippocampus tissue, rat hippocampus tissue.

Concentration

1 mg/mL

Dilution

WB: 1:5,000 ;IHC-P: 1:500-1:1,000 ;IF-Tissue: 1:200-1:500 ;IHC-Fr: 1:200-1:500 ;mIHC: 1:1,000-1:10,000 ;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 50 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes