PI 3 Kinase p55 gamma Recombinant Rabbit Monoclonal Antibody [SR44-06]

About this product

Phosphatidylinositol 3-kinase is a lipid kinase that phosphorylates the inositol ring of phosphatidylinositol and related compounds at the 3’ position. PI 3-kinase p55γ (PIK3R3) is comprised of a catalytic subunit and a regulatory subunit. The human p55γ protein is composed of a rare amino terminal region followed by a proline-rich motif and two Src homology 2 (SH2) domains. PI 3-kinase p55γ mRNAs are expressed in most human fetal and adult tissues; predominant expression is observed in the adult testis. Splice variant (s) of PI 3-kinase p55γ have been identified; one of which has a deletion of 36 amino acids at the amino terminus and another which has an insertion of 59 amino acids at position 256 between the SH2 domains. Research suggests that PI 3-kinase p55γ interacts with the IGFIR (Insulin-like growth factor-I receptor) and IR (Insulin receptor) and may be involved in PI 3-kinase activation by these receptors.

Specifications

Catalog number

ET1602-27

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

DKFZp686P05226 antibody FLJ41892 antibody OTTHUMP00000009783 antibody OTTHUMP00000009786 antibody p55 antibody p55 gamma antibody P55G_HUMAN antibody p55PIK antibody Phosphatidylinositol 3 kinase regulatory subunit gamma antibody Phosphatidylinositol 3 kinase regulatory subunit polypeptide 3 antibody Phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55, gamma) antibody Phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma antibody Phosphatidylinositol 3-kinase regulatory subunit gamma antibody Phosphoinositide 3 kinase regulatory subunit 3 (gamma) antibody Phosphoinositide 3 kinase regulatory subunit 3 antibody Phosphoinositide 3 kinase regulatory subunit polypeptide 3 antibody Phosphoinositide 3 kinase, regulatory subunit 3 (p55, gamma) antibody Phosphoinositide 3 kinase, regulatory subunit, polypeptide 3 (p55, gamma) antibody PI3 kinase p85 subunit gamma antibody PI3-kinase regulatory subunit gamma antibody PI3-kinase subunit p55-gamma antibody PI3K regulatory subunit gamma antibody Pik3r3 antibody PtdIns 3 kinase p85 gamma antibody PtdIns-3-kinase regulatory subunit gamma antibody PtdIns-3-kinase regulatory subunit p55-gamma antibody

Abbreviation

PI3-kinase regulatory subunit gamma, PI3K regulatory subunit gamma, PtdIns-3-kinase regulatory subunit gamma, PI3-kinase subunit p55-gamma, PtdIns-3-kinase regulatory subunit p55-gamma

Swiss Prot

Q92569 Human, Q64143 Mouse, Q63789 Rat

Cellular Locus

Cytosol.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human PI 3 Kinase p55 gamma aa 412-461 / 461.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P

Positive Control

MCF-7 cell lysate, Jurkat cell lysate, human tonsil tissue lysate, PC-3M, SH-SY5Y, mouse testis tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500;IF-Cell: 1:50;IF-Tissue: 1:50;IHC-P: 1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 54 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes