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Product details

MEK1/2 Recombinant Rabbit Monoclonal Antibody [SR13-07]

Catalog number ET1602-3

Price for ET1602-3

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Size / count 100 µL

About this product

A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the Thr-Glu-Tyr motif of ERK. A second MEK family member, MEK-2, resembles MEK-1 in its substrate specificity. MEK-3 (or MKK-3) functions to activate p38 MAP kinase, and MEK-4 (also called SEK1 or MKK-4) activates both p38 and JNK MAP kinases. MEK-5 appears to specifically phosphorylate ERK5, whereas MEK-6 phosphorylates p38 and p38b. MEK-7 (or MKK-7) phosphorylates and activates the JNK signal transduction pathway.

Specifications

Catalog number
ET1602-3
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
AA589381 antibody CFC3 antibody Dual specificity mitogen-activated protein kinase kinase 1 antibody Dual specificity mitogen-activated protein kinase kinase 2 antibody EC 2.7.12.2 antibody ERK activator kinase 1 antibody ERK activator kinase 2 antibody FLJ26075 antibody MAP kinase kinase 1 antibody MAP kinase kinase 2 antibody MAP2K1 antibody MAP2K2 antibody MAPK/ERK kinase 1 antibody MAPK/ERK kinase 2 antibody MAPKK 1 antibody MAPKK1 antibody MAPKK2 antibody MEK 1 antibody MEK1 antibody MEKK1 antibody Mitogen activated protein kinase kinase 1 antibody Mitogen activated protein kinase kinase 2 antibody Mitogen-activated protein kinase kinase 2, p45 antibody MK2 antibody MKK 1 antibody MKK 2 antibody MKK1 antibody MKK2 antibody MP2K1_HUMAN antibody PRKMK 1 antibody PRKMK 2 antibody Prkmk1 antibody Prkmk2 antibody protein kinase, mitogen-activated, kinase 1 (MAP kinase kinase 1) antibody Protein kinase, mitogen-activated, kinase 1 antibody Protein kinase, mitogen-activated, kinase 2 antibody
Abbreviation
MAP kinase kinase 1, MAPKK 1, MKK1, MEK 1, MAP kinase kinase 2, MAPKK 2, MEK 2
Swiss Prot
P36507 Human, Q02750 Human, P31938 Mouse, Q63932 Mouse, P36506 Rat, Q01986 Rat
Cellular Locus
Cytoplasm, Nucleus, Membrane, Mitochondrion
Host
Rabbit
Species Reactivity
Human, Mouse, Rat, Zebrafish
Immunogen
Recombinant protein within Human MEK1 aa 1-393 / 393.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Positive Control
HeLa cell lysate, HepG2 cell lysate, A431 cell lysate, NIH/3T3 cell lysate, mouse brain tissue lysate, PC-12 cell lysate, A549, NIH/3T3, human kidney tissue, mouse lung tissue, mouse kidney tissue, mouse hippocampus tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:5,000 ;IF-Cell: 1:50 ;IF-Tissue: 1:50 ;IHC-P: 1:200 ;IP: Use at an assay dependent concentration. ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 44 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for MEK1/2 Recombinant Rabbit Monoclonal Antibody [SR13-07]?

The catalog number for MEK1/2 Recombinant Rabbit Monoclonal Antibody [SR13-07] is ET1602-3.

What sizes are available for MEK1/2 Recombinant Rabbit Monoclonal Antibody [SR13-07]?

MEK1/2 Recombinant Rabbit Monoclonal Antibody [SR13-07] is available in the following size(s): 100 µL.

Is MEK1/2 Recombinant Rabbit Monoclonal Antibody [SR13-07] in stock?

MEK1/2 Recombinant Rabbit Monoclonal Antibody [SR13-07] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MEK1/2 Recombinant Rabbit Monoclonal Antibody [SR13-07] used for?

A family of protein kinases located upstream of the MAP kinases and responsible for their activation has been identified. The prototype member of this family, designated MAP kinase kinase, or MEK-1, specifically phosphorylates the MAP kinase regulatory threonine and tyrosine residues present in the

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

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