• Certified Lab Equipment & Reagents
  • Fast Dispatch on In-Stock Items
  • Expert Scientific Support

Product details

Histone H2A (hydroxyl Y39) Recombinant Rabbit Monoclonal Antibody [SR4-17]

Catalog number ET1602-35

Price for ET1602-35

Sign In for Pricing

Size / count 100 µL

About this product

Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form the octamer; formed of two H2A-H2B dimers and two H3-H4 dimers, forming two nearly symmetrical halves by tertiary structure. Over 80% of nucleosomes contain the linker Histone H1, derived from an intronless gene, that interacts with linker DNA between nucleosomes and mediates compaction into higher order chromatin. Histones are subject to posttranslational modification by enzymes primarily on their N-terminal tails, but also in their globular domains. Such modifications include methylation, citrullination, acetylation, phosphorylation, sumoylation, ubiquitination and ADP-ribosylation.

Specifications

Catalog number
ET1602-35
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
H2A/m antibody H2A1B_HUMAN antibody HIST1H2AE antibody Histone H2A type 1-B/E antibody Histone H2A.2 antibody Histone H2A.m antibody Histone H2A/a antibody Histone H2A/m antibody
Abbreviation
H2A2, HIST1H2AB, HIST1H2AC, HIST1H2AJ
Swiss Prot
P04908 Human, P28001 Human, Q93077 Human, P35065 Human, Q99878 Human, C0HKE6 Mouse, C0HKE1 Mouse, P02262 Rat
Cellular Locus
Chromosome, Nucleosome core, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within Human Histone H2A aa 1-83 / 130 (hydroxyl Y39) conjugated to Keyhole Limpet Haemocyanin (KLH).
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Hela cell lysate, NIH/3T3 cell lysate, human tonsil tissue, human colon carcinoma tissue, mouse testis tissue, mouse colon tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500 ;IHC-P: 1:50
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 14 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Histone H2A (hydroxyl Y39) Recombinant Rabbit Monoclonal Antibody [SR4-17]?

The catalog number for Histone H2A (hydroxyl Y39) Recombinant Rabbit Monoclonal Antibody [SR4-17] is ET1602-35.

What sizes are available for Histone H2A (hydroxyl Y39) Recombinant Rabbit Monoclonal Antibody [SR4-17]?

Histone H2A (hydroxyl Y39) Recombinant Rabbit Monoclonal Antibody [SR4-17] is available in the following size(s): 100 µL.

Is Histone H2A (hydroxyl Y39) Recombinant Rabbit Monoclonal Antibody [SR4-17] in stock?

Histone H2A (hydroxyl Y39) Recombinant Rabbit Monoclonal Antibody [SR4-17] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Histone H2A (hydroxyl Y39) Recombinant Rabbit Monoclonal Antibody [SR4-17] used for?

Eukaryotic histones are basic and water soluble nuclear proteins that form hetero-octameric nucleosome particles by wrapping 146 base pairs of DNA in a left-handed super-helical turn sequentially to form chromosomal fiber. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form t

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

You Might Also Like
CD8 (RIV11), CF555 conjugate, 0.1mg/mL
CD8 (RIV11), CF555 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC550333-500
TNF alpha (J2D10), CF405S conjugate, 0.1mg/mL
TNF alpha (J2D10), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040994-100
CD5 (Cris-1), CF740 conjugate, 0.1mg/mL
CD5 (Cris-1), CF740 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC740176-500
Cytokeratin 10 (KRT10/844), CF488A conjugate, 0.1mg/mL
Cytokeratin 10 (KRT10/844), CF488A conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC880844-500
Vimentin (VM1170), CF647 conjugate, 0.1mg/mL
Vimentin (VM1170), CF647 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC471170-500
CD27 (Tumor Necrosis Factor Receptor Superfamily 7) (rLPFS2/1611), CF405S conjugate, 0.1mg/mL
CD27 (Tumor Necrosis Factor Receptor Superfamily 7) (rLPFS2/1611), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC041976-500
MCM7 (Proliferation Marker) (MCM7/1468), CF568 conjugate, 0.1mg/mL
MCM7 (Proliferation Marker) (MCM7/1468), CF568 conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC681468-500
Moesin (MSN/492), CF405S conjugate, 0.1mg/mL
Moesin (MSN/492), CF405S conjugate, 0.1mg/mL
By Afraxis
Sign In for Pricing
Ref: BNC040492-500