MMP-12 Recombinant Rabbit Monoclonal Antibody [SR03-23] — image 1 of 3

Product details

MMP-12 Recombinant Rabbit Monoclonal Antibody [SR03-23]

Catalog number ET1602-42

Discontinued

Price for ET1602-42

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-12 (also designated macrophage metalloelastase) is produced in alveolar macrophages and degrades elastin. MMP-12 may contribute to elastin degradation occurring in granulomatous skin diseases and may also participate in macrophage migration through the epidermal and vascular basement membranes in inflammatory disorders.

Specifications

Catalog number: ET1602-42
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9000-83-3
Product Name Alternative: EC 3.4.24.65 antibody HME antibody Macrophage elastase antibody Macrophage metalloelastase antibody Macrophage metaloelastase antibody Matrix metallopeptidase 12 (macrophage elastase) antibody Matrix metalloprotease 12 antibody Matrix metalloproteinase-12 antibody ME antibody MGC138506 antibody MME antibody MMP 12 antibody MMP-12 antibody Mmp12 antibody MMP12_HUMAN antibody
Abbreviation: MME, ME, hME, MMP-12
Swiss Prot: P39900 Human, P34960 Mouse, Q63341 Rat
Cellular Locus: Secreted.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human MMP12 aa 421-470 / 470.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Positive Control: A549 cell lysate, Hela cell lysate, MCF-7 cell lysate, THP-1 cell lysate, human breast carcinoma tissue lysate, mouse lung tissue lysate, rat lung tissue lysate.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:20-1:50 ;IF-Tissue: 1:20-1:50 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 54 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for MMP-12 Recombinant Rabbit Monoclonal Antibody [SR03-23]?

The catalog number for MMP-12 Recombinant Rabbit Monoclonal Antibody [SR03-23] is ET1602-42.

Is MMP-12 Recombinant Rabbit Monoclonal Antibody [SR03-23] in stock?

MMP-12 Recombinant Rabbit Monoclonal Antibody [SR03-23] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MMP-12 Recombinant Rabbit Monoclonal Antibody [SR03-23] used for?

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.