Active Caspase-3 Recombinant Rabbit Monoclonal Antibody [SR01-02] — image 1 of 3

Product details

Active Caspase-3 Recombinant Rabbit Monoclonal Antibody [SR01-02]

Catalog number ET1602-47

Discontinued

Price for ET1602-47

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Caspase-3 is a caspase protein that interacts with caspase-8 and caspase-9. It is encoded by the CASP3 gene. CASP3 orthologs have been identified in numerous mammals for which complete genome data are available. Unique orthologs are also present in birds, lizards, lissamphibians, and teleosts. Caspase-3 shares many of the typical characteristics common to all currently-known caspases. For example, its active site contains a cysteine residue (Cys-163) and histidine residue (His-121) that stabilize the peptide bond cleavage of a protein sequence to the carboxy-terminal side of an aspartic acid when it is part of a particular 4-amino acid sequence. This specificity allows caspases to be incredibly selective, with a 20,000-fold preference for aspartic acid over glutamic acid. A key feature of caspases in the cell is that they are present as zymogens, termed procaspases, which are inactive until a biochemical change causes their activation. Each procaspase has an N-terminal large subunit of about 20 kDa followed by a smaller subunit of about 10 kDa, called p20 and p10, respectively.

Specifications

Catalog number: ET1602-47
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9000-83-3
Product Name Alternative: Caspase3 A830040C14Rik antibody Apopain antibody CASP 3 antibody CASP-3 antibody CASP3 antibody CASP3_HUMAN antibody Casp3a antibody Caspase 3 antibody Caspase 3, apoptosis-related cysteine peptidase antibody Caspase 3, apoptosis-related cysteine protease antibody Caspase 3, apoptosis-related cysteine protease a antibody Caspase-3 subunit p12 antibody Caspase3 antibody CC3 antibody CPP 32 antibody CPP-32 antibody CPP32 antibody CPP32B antibody Cysteine protease CPP32 antibody EC 3.4.22.56 antibody ICE3 antibody LICE antibody mldy antibody OTTHUMP00000165052 antibody OTTHUMP00000165053 antibody OTTHUMP00000165054 antibody PARP cleavage protease antibody Procaspase3 antibody Protein Yama antibody SCA 1 antibody SCA-1 antibody SCA1 antibody SREBP cleavage activity 1 antibody Yama antibody Yama protein antibody
Abbreviation: CASP-3, CPP-32, SCA-1
Swiss Prot: P42574 Human
Cellular Locus: Cytoplasm
Host: Rabbit
Species Reactivity: Human, Pig
Immunogen: Synthetic peptide within Human Caspase-3 aa 28-67 / 277.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P
Positive Control: Camptothecin (2 μM) treated Jurkat cell lysate, Hela, PC-3M, human colon carcinoma tissue, human placenta tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 17 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Active Caspase-3 Recombinant Rabbit Monoclonal Antibody [SR01-02]?

The catalog number for Active Caspase-3 Recombinant Rabbit Monoclonal Antibody [SR01-02] is ET1602-47.

Is Active Caspase-3 Recombinant Rabbit Monoclonal Antibody [SR01-02] in stock?

Active Caspase-3 Recombinant Rabbit Monoclonal Antibody [SR01-02] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Active Caspase-3 Recombinant Rabbit Monoclonal Antibody [SR01-02] used for?

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.