Caveolin-1 Recombinant Rabbit Monoclonal Antibody [SZ02-01]

About this product

Caveolae (also known as plasmalemmal vesicles) are 50-100 nM flask-shaped membranes that represent a subcompartment of the plasma membrane. On the basis of morphological studies, caveolae have been implicated to function in the transcytosis of various macromolecules (including LDL) across capillary endothelial cells, uptake of small molecules via potocytosis and the compartmentalization of certain signaling molecules including G protein-coupled receptors. Three proteins, caveolin-1, caveolin-2 and caveolin-3, have been identified as principal components of caveolae. Two forms of caveolin-1, designated alpha and beta, share a distinct but overlapping cellular distribution and differ by an amino terminal 31 amino acid sequence which is absent from the beta isoform. Caveolin-1 shares 31% identity with caveolin-2 and 65% identity with caveolin-3 at the amino acid level. Functionally, the three proteins differ in their interactions with heterotrimeric G protein isoforms.

Specifications

Catalog number

ET1603-1

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

BSCL3 antibody CAV antibody CAV1 antibody CAV1_HUMAN antibody caveolae protein, 22 kD antibody caveolin 1 alpha isoform antibody caveolin 1 beta isoform antibody Caveolin 1 caveolae protein 22kDa antibody Caveolin-1 antibody Caveolin1 antibody cell growth-inhibiting protein 32 antibody CGL3 antibody LCCNS antibody MSTP085 antibody OTTHUMP00000025031 antibody PPH3 antibody VIP 21 antibody VIP21 antibody

Abbreviation

CAV1, CAV

Swiss Prot

Q03135 Human, P49817 Mouse, P41350 Rat

Cellular Locus

Golgi apparatus membrane, Cell membrane, Membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human Caveolin-1 aa 129-178 / 178.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P

Positive Control

A549 cell lysate, A431 cell lysate, human lung tissue lysate, mouse lung tissue lysate, mouse heart tissue lysate, rat lung tissue lysate, rat heart tissue lysate, A549, MCF-7, NIH/3T3, human lung tissue, human liver tissue, human liver carcinoma tissue, human uterus tissue, mouse lung tissue, mouse liver tissue, mouse heart tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:5,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 20 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes