RNF20 Recombinant Rabbit Monoclonal Antibody [SP00-47] — image 1 of 3

Product details

RNF20 Recombinant Rabbit Monoclonal Antibody [SP00-47]

Catalog number ET1604-4

Price for ET1604-4

Size / count 100 µL

About this product

Ubiquitination is an important mechanism through which three classes of enzymes act in concert to target short-lived or abnormal proteins for destruction. The three classes of enzymes involved in ubiquitination are the ubiquitin-activating enzymes (E1s), the ubiquitin-conjugating enzymes (E2s) and the ubiquitin-protein ligases (E3s). RNF20 (ring finger protein 20), also known as BRE1, BRE1A or hBRE1, is a 975 amino acid nuclear protein that belongs to the BRE1 family. As a component of the RNF20/40 complex, RNF20 functions as an E3 ubiquitin-protein ligase that regulates the monoubiquitination and subsequent degradation of select residues on target proteins, such as Histone H2B. RNF20 is required for transcriptional activation of Hox genes and is most likely recruited by p53 to the MDM2 promoter, thereby acting as a transcriptional co-activator. RNF20 contains one zinc finger domain and exists as a homodimer.

Specifications

Catalog number: ET1604-4
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: BRE1 A antibody BRE1 antibody BRE1 E3 ubiquitin ligase homolog antibody BRE1-A antibody BRE1A antibody BRE1A_HUMAN antibody E3 ubiquitin-protein ligase BRE1A antibody hBRE1 antibody Homolog of S. cerevisiae BRE1 antibody RING finger protein 20 antibody Ring finger protein 20 E3 ubiquitin protein ligase antibody Rnf20 antibody
Abbreviation: BRE1-A, hBRE1, BRE1A
Swiss Prot: Q5VTR2 Human, Q5DTM8 Mouse
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within human RNF20 aa 480-585/975.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, FC, IF-Cell
Positive Control: HeLa cell lysate, MCF7 cell lysate, C2C12 cell lysate, A549.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 114 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for RNF20 Recombinant Rabbit Monoclonal Antibody [SP00-47]?

The catalog number for RNF20 Recombinant Rabbit Monoclonal Antibody [SP00-47] is ET1604-4.

What sizes are available for RNF20 Recombinant Rabbit Monoclonal Antibody [SP00-47]?

RNF20 Recombinant Rabbit Monoclonal Antibody [SP00-47] is available in the following size(s): 100 µL.

Is RNF20 Recombinant Rabbit Monoclonal Antibody [SP00-47] in stock?

RNF20 Recombinant Rabbit Monoclonal Antibody [SP00-47] is currently made to order / not held in immediate stock. Contact us for lead time.

What is RNF20 Recombinant Rabbit Monoclonal Antibody [SP00-47] used for?

Is this product species cross-reactive?

Cross-reactivity data, based on available testing, is listed under the reactivity section of the datasheet. Contact us if you need reactivity confirmed for a species not listed.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.