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Product details

ALDH1A1 Recombinant Rabbit Monoclonal Antibody [SY11-02]

Catalog number ET1605-24

Price for ET1605-24

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Size / count 100 µL

About this product

Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1), aldehyde dehydrogenase family 1 member A1, aldehyde dehydrogenase cytosolic, ALDHII, ALDH-E1 or ALDH E1, is a retinal dehydrogenase that participates in the biosynthesis of retinoic acid (RA). There are two major liver isoforms of ALDH1 that can localize to cytosolic or mitochondrial space. The ALDH1A2 (RALDH2, RALDH2-T) gene produces three different transcripts and also catalyzes the synthesis of RA from retinaldehyde. ALDH1A3 (ALDH6, RALDH3, ALDH1A6) is a 37 kb gene that consists of 13 exons and produces a major transcript of approximately 3.5 kb most abundant in salivary gland, stomach and kidney. ALDH3A1 (stomach type, ALDH3, ALDHIII) forms a cytoplasmic homodimer that preferentially oxidizes aromatic aldehyde substrates. ALDH genes upregulate as a part of the oxidative stress response, and appear to be abundant in certain tumors that have an accelerated metabolism toward chemotherapy agents.

Specifications

Catalog number
ET1605-24
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Acetaldehyde dehydrogenase 1 antibody AHD2 antibody AL1A1_HUMAN antibody ALDC antibody Aldehyde dehydrogenase 1 family member A1 antibody Aldehyde dehydrogenase 1 soluble antibody Aldehyde dehydrogenase 1A1 antibody Aldehyde dehydrogenase antibody Aldehyde dehydrogenase cytosolic antibody Aldehyde dehydrogenase family 1 member A1 antibody Aldehyde dehydrogenase liver cytosolic antibody ALDH 1 antibody ALDH 1A1 antibody ALDH class 1 antibody ALDH, liver cytosolic antibody ALDH-E1 antibody ALDH1 A1 antibody ALDH1 antibody ALDH11 antibody ALDH1A1 antibody ALHDII antibody cytosolic antibody epididymis luminal protein 12 antibody epididymis luminal protein 9 antibody epididymis secretory sperm binding protein Li 53e antibody HEL-S-53e antibody MGC2318 antibody PUMB1 antibody RALDH 1 antibody RalDH1 antibody Retinal dehydrogenase 1 antibody
Abbreviation
RALDH 1, RalDH1, ALDH1A1
Swiss Prot
P00352 Human, P24549 Mouse, P51647 Rat
Cellular Locus
Cytoplasm,Cell projection.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human ALDH1A1 aa 300-360.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, IP
Positive Control
A549 cell lysate, mouse lung tissue lysate, human liver tissue lysate, human kidney tissue lysate, human liver tissue, human kidney tissue, mouse striatum tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC-P: 1:100-1:200 ;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 55 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for ALDH1A1 Recombinant Rabbit Monoclonal Antibody [SY11-02]?

The catalog number for ALDH1A1 Recombinant Rabbit Monoclonal Antibody [SY11-02] is ET1605-24.

What sizes are available for ALDH1A1 Recombinant Rabbit Monoclonal Antibody [SY11-02]?

ALDH1A1 Recombinant Rabbit Monoclonal Antibody [SY11-02] is available in the following size(s): 100 µL.

Is ALDH1A1 Recombinant Rabbit Monoclonal Antibody [SY11-02] in stock?

ALDH1A1 Recombinant Rabbit Monoclonal Antibody [SY11-02] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ALDH1A1 Recombinant Rabbit Monoclonal Antibody [SY11-02] used for?

Aldehyde dehydrogenases (ALDHs) mediate NADP+-dependent oxidation of aldehydes into acids during the detoxification of alcohol-derived acetaldehyde; metabolism of corticosteroids, biogenic amines and neurotransmitters; and lipid peroxidation. ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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