FUBP1 Recombinant Rabbit Monoclonal Antibody [SY11-04]

About this product

Activation of FUSE, the far upstream element, is required for the proper ex-pression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP1 (FUSE-binding protein or far upstream element-binding protein) to FUSE is necessary for c-Myc expression, indicating that FBP1 functions as a growth-dependent regulator of c-Myc expression. Isolated from proliferating HL-60 cells, FBP1 (FBP), FBP2 and FBP3 comprise a family of single-stranded DNA-binding proteins that specifically bind to FUSE elements. The FBP transcription factors share a conserved central DNA-binding domain and show significant homology in their carboxyl-terminal activation domains. Expression of FBP1 is detected in undifferentiated cells and is substantially decreased following cellular differentiation.

Specifications

Catalog number

ET1605-26

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

DNA helicase V antibody far upstream element (FUSE) binding protein 1 antibody Far upstream element (FUSE) binding protein 4 antibody Far upstream element binding protein 1 antibody far upstream element binding protein antibody Far upstream element-binding protein 1 antibody FBP antibody FUBP antibody Fubp1 antibody FUBP1_HUMAN antibody Fubp4 antibody FUSE binding protein 1 antibody FUSE-binding protein 1 antibody HDH V antibody

Abbreviation

FBP, FUSE-binding protein 1, hDH V, FUBP1

Swiss Prot

Q96AE4 Human, Q91WJ8 Mouse, Q32PX7 Rat

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human FUBP1 aa 584-633 / 644.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, FC

Positive Control

Hela cell lysate, Raji cell lysate, Hela, MCF-7, HepG2, human breast carcinoma tissue, human pancreas tissue, mouse brain tissue, human tonsil tissue, mouse stomach tissue, mouse pancreas tissue, Jurkat.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000;IF-Cell: 1:100-1:500;IF-Tissue: 1:100-1:500;IHC-P: 1:50-1:200;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

68 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes