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Product details

STAT3 Recombinant Rabbit Monoclonal Antibody [SY34-01]

Catalog number ET1605-45

Price for ET1605-45

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Size / count 100 µL

About this product

Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part of the ISGF3 transcription factor complex. Although early reports indicate Stat3 activation by EGF and IL-6, it has been shown that Stat3β appears to be activated by both while Stat3α is activated by EGF, but not by IL-6. Highest expression of Stat4 is seen in testis and myeloid cells. IL-12 has been identified as an activator of Stat4. Stat5 has been shown to be activated by Prolactin and by IL-3. Stat6 is involved in IL-4 activated signaling pathways.

Specifications

Catalog number
ET1605-45
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
1110034C02Rik antibody Acute Phase Response Factor antibody Acute-phase response factor antibody ADMIO antibody APRF antibody AW109958 antibody DNA binding protein APRF antibody FLJ20882 antibody HIES antibody MGC16063 antibody Signal transducer and activator of transcription 3 (acute phase response factor) antibody Signal transducer and activator of transcription 3 antibody STAT 3 antibody Stat3 antibody STAT3_HUMAN antibody
Abbreviation
STAT3
Swiss Prot
P40763 Human, P42227 Mouse, P52631 Rat
Cellular Locus
Cytoplasm, Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within C-terminal human STAT3.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control
HeLa cell lysate, HaCaT cell lysate, Mouse brain tissue lysate, Rat brain tissue lysate, Rat kidney tissue lysate, HeLa, NIH/3T3, human stomach carcinoma tissue, human breast carcinoma tissue, mouse brain tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IF-Cell: 1:100 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:50-1:1,000 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 88 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for STAT3 Recombinant Rabbit Monoclonal Antibody [SY34-01]?

The catalog number for STAT3 Recombinant Rabbit Monoclonal Antibody [SY34-01] is ET1605-45.

What sizes are available for STAT3 Recombinant Rabbit Monoclonal Antibody [SY34-01]?

STAT3 Recombinant Rabbit Monoclonal Antibody [SY34-01] is available in the following size(s): 100 µL.

Is STAT3 Recombinant Rabbit Monoclonal Antibody [SY34-01] in stock?

STAT3 Recombinant Rabbit Monoclonal Antibody [SY34-01] is currently made to order / not held in immediate stock. Contact us for lead time.

What is STAT3 Recombinant Rabbit Monoclonal Antibody [SY34-01] used for?

Membrane receptor signaling by various ligands, including interferons and growth hormones such as EGF, induces activation of JAK kinases which then leads to tyrosine phosphorylation of the various Stat transcription factors. Stat1 and Stat2 are induced by IFN-α and form a heterodimer which is part o

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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