Dnmt3b Recombinant Rabbit Monoclonal Antibody [SY09-07]

Catalog number ET1605-9

Price for ET1605-9

Size / count 100 µL

About this product

Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, and this methylation results in transcriptional repression of the target gene. The Dnmt enzymes are encoded by independent genes. Dnmt1 is the most abundant, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development. Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3. Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, is expressed at substantially lower levels in adult tissues, and is likely involved in methylating newly integrated retroviral DNA. Dnmt3a and Dnmt3b are encoded by two distinct genes, but both are abundantly expressed in embryonic stem cells, where they also methylate CpG motifs on DNA.

Specifications

Catalog number: ET1605-9
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Cytosine 5methyltransferase 3B antibody DNA antibody DNA (cytosine 5) methyltransferase 3 beta antibody DNA (cytosine 5)-methyltransferase 3B antibody DNA (cytosine-5)-methyltransferase 3B antibody DNA methyltransferase HsaIIIB antibody DNA MTase HsaIIIB antibody DNM3B_HUMAN antibody Dnmt3b antibody EC 2.1.1.37 antibody ICF antibody ICF1 antibody M.HsaIIIB antibody MGC124407 antibody RP23-89H14.3 antibody
Abbreviation: Dnmt3b, DNA MTase HsaIIIB, M.HsaIIIB, DNMT3B
Swiss Prot: Q9UBC3 Human, O88509 Mouse
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human Dnmt3b aa 61-110 / 853.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB
Positive Control: NCCIT cell lysates.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 96 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Dnmt3b Recombinant Rabbit Monoclonal Antibody [SY09-07]?

The catalog number for Dnmt3b Recombinant Rabbit Monoclonal Antibody [SY09-07] is ET1605-9.

What sizes are available for Dnmt3b Recombinant Rabbit Monoclonal Antibody [SY09-07]?

Dnmt3b Recombinant Rabbit Monoclonal Antibody [SY09-07] is available in the following size(s): 100 µL.

Is Dnmt3b Recombinant Rabbit Monoclonal Antibody [SY09-07] in stock?

Dnmt3b Recombinant Rabbit Monoclonal Antibody [SY09-07] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Dnmt3b Recombinant Rabbit Monoclonal Antibody [SY09-07] used for?

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.