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Product details

Calponin Recombinant Rabbit Monoclonal Antibody [SI67-01]

Catalog number ET1606-17

Price for ET1606-17

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Size / count 100 µL

About this product

Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contraction through its interaction with F-Actin and inhibition of the Actin-activated MgATPase activity of phosphorylated Myosin. Both properties are lost following phosphorylation (primarily at Serine 175) by protein kinase C or calmodulin-dependent protein kinase II. The three forms of Calponin, Calponin 1 (basic Calponin), Calponin 2 (neutral Calponin) and Calponin 3 (acidic Calponin), are found in smooth muscle tissue. Additionally, Calponin 2 is found in heart muscle tissue and Calponin 3 is found in the brain.

Specifications

Catalog number
ET1606-17
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Basic calponin antibody Calponin 1 antibody Calponin 1 basic smooth muscle antibody Calponin H1 antibody Calponin H1 smooth muscle antibody Calponin-1 antibody Calponin1 antibody Calponins basic antibody CNN 1 antibody Cnn1 antibody CNN1_HUMAN antibody Epididymis secretory protein Li 14 antibody HEL S 14 antibody Sm Calp antibody SMCC antibody smooth muscle antibody
Abbreviation
CNN1
Swiss Prot
P51911 Human, Q08091 Mouse, Q08290 Rat
Cellular Locus
Cytoskeleton,focal adhesion.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Calponin aa 248-297 / 297.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IF-Tissue, IHC-P
Positive Control
Mouse stomach tissue lysate, Rat stomach tissue lysate, Hela cell lysate, NIH/3T3 cell lysate, HepG2, mouse colon tissue, rat colon tissue, rat stomach tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:5,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 33 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Calponin Recombinant Rabbit Monoclonal Antibody [SI67-01]?

The catalog number for Calponin Recombinant Rabbit Monoclonal Antibody [SI67-01] is ET1606-17.

What sizes are available for Calponin Recombinant Rabbit Monoclonal Antibody [SI67-01]?

Calponin Recombinant Rabbit Monoclonal Antibody [SI67-01] is available in the following size(s): 100 µL.

Is Calponin Recombinant Rabbit Monoclonal Antibody [SI67-01] in stock?

Calponin Recombinant Rabbit Monoclonal Antibody [SI67-01] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Calponin Recombinant Rabbit Monoclonal Antibody [SI67-01] used for?

Calponin regulates smooth muscle cell contraction and is a marker of smooth muscle cell differentiation. Calponin, an Actin- and Tropomyosin-binding protein, is characterized as an inhibitory factor of smooth-muscle actomyosin activity. Calponin is implicated in the regulation of smooth muscle contr

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

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