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Product details

Lamin B1 Recombinant Rabbit Monoclonal Antibody [SI17-07]

Catalog number ET1606-27

Price for ET1606-27

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Size / count 100 µL

About this product

A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Nuclear lamins are critical to maintaining the integrity of the nuclear envelope and cellular morphology as components of the nuclear lamina, a fibrous layer on the nucleoplasmic side of the inner nuclear membrane, which is thought to provide a framework for the nuclear envelope and may also interact with chromatin. B-type lamins undergo a series of modifications, such as farnesylation and phosphorylation. Increased phosphorylation of the lamins occurs before envelope disintegration and probably plays a role in regulating lamin associations. Nuclear Lamin B is fragmented as a consequence of apoptosis by an unidentified member of the ICE family.

Specifications

Catalog number
ET1606-27
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
ADLD antibody lamin B1 antibody Lamin-B1 antibody LMN antibody LMN2 antibody LMNB antibody Lmnb1 antibody LMNB1_HUMAN antibody MGC111419 antibody OTTHUMP00000159218 antibody
Abbreviation
LMNB1
Swiss Prot
P20700 Human, P14733 Mouse, P70615 Rat
Cellular Locus
Nucleus inner membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Lamin B1 aa 511-560 / 586.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Tissue, IHC-P, CUT&Tag-seq
Positive Control
Hela cell lysate, Jurkat cell lysate, NIH/3T3 cell lysate, human liver tissue, human colon carcinoma tissue, human breast carcinoma tissue, mouse colon tissue, mouse brain tissue, PC-12 cell lysate, human lymph nodes tissue, mouse large intestine tissue, HepG2.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5,000 ;IHC-P: 1:500-1:1,000 ;IF-Tissue: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 66 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Lamin B1 Recombinant Rabbit Monoclonal Antibody [SI17-07]?

The catalog number for Lamin B1 Recombinant Rabbit Monoclonal Antibody [SI17-07] is ET1606-27.

What sizes are available for Lamin B1 Recombinant Rabbit Monoclonal Antibody [SI17-07]?

Lamin B1 Recombinant Rabbit Monoclonal Antibody [SI17-07] is available in the following size(s): 100 µL.

Is Lamin B1 Recombinant Rabbit Monoclonal Antibody [SI17-07] in stock?

Lamin B1 Recombinant Rabbit Monoclonal Antibody [SI17-07] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Lamin B1 Recombinant Rabbit Monoclonal Antibody [SI17-07] used for?

A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease family. This family, termed Ced-3/ICE, functions as key components of the apoptotic machinery and act to destroy specific target proteins whic

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

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