MMP-14 Recombinant Rabbit Monoclonal Antibody [SJ18-09] — image 1 of 3

Product details

MMP-14 Recombinant Rabbit Monoclonal Antibody [SJ18-09]

Catalog number ET1606-48

Discontinued

Price for ET1606-48

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. Membrane-type matrix metalloproteinases, including MT-MMP-1 (also designated MMP-14), MT-MMP-2 (also designated MMP-15), MT-MMP-3 (also designated MMP-16) and MT-MMP-4 (also designated MMP-17) are type I membrane proteins that function to activate other MMPs. MT-MMP activation appears to be mediated by members of the proprotein convertase family, suggesting that a proprotein convertase/MT-MMP/MMP cascade may be involved in the regulation of ECM turnover.

Specifications

Catalog number: ET1606-48
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9000-83-3
Product Name Alternative: Matrix metallopeptidase 14 (membrane inserted) antibody Matrix metalloproteinase 14 antibody Matrix metalloproteinase-14 antibody Membrane type 1 matrix metalloproteinase antibody Membrane type 1 metalloprotease antibody Membrane type matrix metalloproteinase 1 antibody Membrane-type matrix metalloproteinase 1 antibody Membrane-type-1 matrix metalloproteinase antibody MMP 14 antibody MMP X1 antibody MMP-14 antibody MMP-X1 antibody Mmp14 antibody MMP14_HUMAN antibody MMPX1 antibody MT MMP 1 antibody MT-MMP 1 antibody MT1 MMP antibody MT1-MMP antibody MT1MMP antibody MTMMP 1 antibody MTMMP1 antibody
Abbreviation: MMP-14, MTMMP1, MT1-MMP, MT1MMP, MT-MMP 1
Swiss Prot: P50281 Human, P53690 Mouse, Q10739 Rat
Cellular Locus: Membrane, Melanosome, Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human MMP14 aa 149-200 / 582.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Positive Control: Human kidney tissue lysates, CRC, BT-20, human breast carcinoma tissue, human kidney tissue, human uterus tissue, A549.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:2000 ;IHC-P: 1:50-1:10,000 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 66 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for MMP-14 Recombinant Rabbit Monoclonal Antibody [SJ18-09]?

The catalog number for MMP-14 Recombinant Rabbit Monoclonal Antibody [SJ18-09] is ET1606-48.

Is MMP-14 Recombinant Rabbit Monoclonal Antibody [SJ18-09] in stock?

MMP-14 Recombinant Rabbit Monoclonal Antibody [SJ18-09] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MMP-14 Recombinant Rabbit Monoclonal Antibody [SJ18-09] used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.