CDC7 Kinase Recombinant Rabbit Monoclonal Antibody [SY21-01] — image 1 of 2

Product details

CDC7 Kinase Recombinant Rabbit Monoclonal Antibody [SY21-01]

Catalog number ET1607-1

Price for ET1607-1

Size / count 100 µL

About this product

Cell division cycle 7-related protein kinase is an enzyme that in humans is encoded by the CDC7 gene. The Cdc7 kinase is involved in regulation of the cell cycle at the point of chromosomal DNA replication. The gene CDC7 appears to be conserved throughout eukaryotic evolution; this means that most eukaryotic cells have the Cdc7 kinase protein. The product encoded by this gene is predominantly localized in the nucleus and is a cell division cycle protein with kinase activity. The protein is a serine-threonine kinase that is activated by another protein called either Dbf4 in the yeast Saccharomyces cerevisiae or ASK in mammals. The Cdc7/Dbf4 complex adds a phosphate group to the minichromosome maintenance (MCM) protein complex allowing for the initiation of DNA replication in mitosis (as explained in the Cdc7 and Replication section below). Although expression levels of the protein appear to be constant throughout the cell cycle, the protein kinase activity appears to increase during S phase. It has been suggested that the protein is essential for initiation of DNA replication and that it plays a role in regulating cell cycle progression. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Additional transcript sizes have been detected, suggesting the presence of alternative splicing.

Specifications

Catalog number: ET1607-1
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Cdc 7 antibody CDC7 antibody CDC7 cell division cycle 7 antibody CDC7 cell division cycle 7 like 1 antibody CDC7 L1 antibody Cdc7 like 1 antibody CDC7 related kinase antibody CDC7-related kinase antibody CDC7_HUMAN antibody CDC7L 1 antibody CDC7L1 antibody Cell division cycle 7 homolog antibody Cell division cycle 7 kinase antibody Cell division cycle 7 like protein 1 antibody Cell division cycle 7 related protein kinase antibody Cell division cycle 7-related protein kinase antibody HsCDC 7 antibody HsCdc7 antibody Hsk 1 antibody Hsk1 antibody HuCDC 7 antibody huCdc7 antibody MGC117361 antibody MGC126237 antibody MGC126238 antibody
Abbreviation: CDC7-related kinase, HsCdc7, huCdc7
Swiss Prot: O00311 Human, Q9Z0H0 Mouse
Cellular Locus: Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human CDC7 Kinase aa 1-50 / 574.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, FC
Positive Control: Jurkat cell lysate, Hela cell lysate, A431.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:5,000 ;FC: 1:50-1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 64 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for CDC7 Kinase Recombinant Rabbit Monoclonal Antibody [SY21-01]?

The catalog number for CDC7 Kinase Recombinant Rabbit Monoclonal Antibody [SY21-01] is ET1607-1.

What sizes are available for CDC7 Kinase Recombinant Rabbit Monoclonal Antibody [SY21-01]?

CDC7 Kinase Recombinant Rabbit Monoclonal Antibody [SY21-01] is available in the following size(s): 100 µL.

Is CDC7 Kinase Recombinant Rabbit Monoclonal Antibody [SY21-01] in stock?

CDC7 Kinase Recombinant Rabbit Monoclonal Antibody [SY21-01] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CDC7 Kinase Recombinant Rabbit Monoclonal Antibody [SY21-01] used for?

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.