Caveolin-2 Recombinant Rabbit Monoclonal Antibody [SY22-05]

About this product

Caveolae (also known as plasmalemmal vesicles) are 50-100 nM flask-shaped membranes that represent a subcompartment of the plasma membrane. On the basis of morphological studies, caveolae have been implicated to function in the transcytosis of various macromolecules (including LDL) across capillary endothelial cells, uptake of small molecules via potocytosis and the compartmentalization of certain signaling molecules including G protein-coupled receptors. Three proteins, caveolin-1, caveolin-2 and caveolin-3, have been identified as principal components of caveolae. Two forms of caveolin-1, designated a and b, share a distinct but overlapping cellular distribution and differ by an N-terminal 31 amino acid sequence that is absent from the b isoform. Caveolin-1 shares 31% identity with caveolin-2 and 65% identity with caveolin-3 at the amino acid level. Functionally, the three proteins differ in their interactions with heterotrimeric G protein isoforms.

Specifications

Catalog number

ET1607-15

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

CAV antibody CAV2 antibody CAV2_HUMAN antibody Caveolae protein 20 kD antibody Caveolin 2 antibody Caveolin 2 isoform a and b antibody Caveolin-2 antibody MGC12294 antibody OTTHUMP00000025032 antibody OTTHUMP00000195982 antibody

Abbreviation

CAV2

Swiss Prot

P51636 Human

Cellular Locus

Cytoplasm, Nucleus, Membrane.

Host

Rabbit

Species Reactivity

Human

Immunogen

Synthetic peptide within Human Caveolin-2 aa 1-50 / 162.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP

Positive Control

HUVEC, Hela, human cervix uteri tissue, human uterus tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:2,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

20 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes