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![Paxillin Recombinant Rabbit Monoclonal Antibody [SY23-02] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea81220/imageurl/et1607-22.webp)
Product details
Catalog number ET1607-22
Price for ET1607-22
Size / count 100 µL
Paxillin is a focal adhesion phosphoprotein that is localized to the cytoskeleton. Phosphorylation of paxillin has been shown to occur in response to PDGF treatment, v-Src transformation or cross-linking of integrins. FAK (focal adhesion kinase) and PYK2 have been shown to phosphorylate paxillin. FAK phosphorylates paxillin specifically on Tyr 118 in vitro. However, FAK phosphorylation does not seem to be required for the recruitment of paxillin to cell adhesion sites. Paxillin may play a role in signal transduction, regulation of cell morphology and the recruitment of structural and signaling molecules to focal adhesions. It has been shown that the amount of paxillin is reduced in mitotic cells by proteolytic downregulation and that paxillin is alternatively phosphorylated on serine rather than on tyrosine and serine during mitosis.
The catalog number for Paxillin Recombinant Rabbit Monoclonal Antibody [SY23-02] is ET1607-22.
Paxillin Recombinant Rabbit Monoclonal Antibody [SY23-02] is available in the following size(s): 100 µL.
Paxillin Recombinant Rabbit Monoclonal Antibody [SY23-02] is currently made to order / not held in immediate stock. Contact us for lead time.
Paxillin is a focal adhesion phosphoprotein that is localized to the cytoskeleton. Phosphorylation of paxillin has been shown to occur in response to PDGF treatment, v-Src transformation or cross-linking of integrins. FAK (focal adhesion kinase) and PYK2 have been shown to phosphorylate paxillin. FA
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