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Product details

CD3 epsilon Recombinant Rabbit Monoclonal Antibody [SY0239]

Catalog number ET1607-29

Price for ET1607-29

Size / count 100 µL

About this product

The T cell antigen receptor (TCR) recognizes foreign antigens and translates such recognition events into intracellular signals that elicit a change in the cell from a dormant to an activated state. Much of this signaling process can be attributed to a multisubunit complex of proteins that associates directly with the TCR. This complex has been designated CD3 (cluster of differentiation 3). CD3 is composed of four polypeptides: ζ, γ, ε and δ. Each of these polypeptides contains at least one immunoreceptor tyrosine-based activation motif (ITAM). Engagement of TCR complex with foreign antigens induces tyrosine phosphorylation in the ITAM motifs and phosphorylated ITAMs function as docking sites for signaling molecules such as ZAP-70 and p85 subunit of PI-3 kinase. TCR ligation also induces a conformational change in CD3ε, such that a proline region is exposed and then associates with the adaptor protein Nck.

Specifications

Catalog number: ET1607-29
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CD3 epsilon antibody CD3e antibody CD3e antigen epsilon polypeptide (TiT3 complex) antibody CD3E antigen epsilon polypeptide antibody CD3E antigen, epsilon subunit antibody CD3e molecule epsilon antibody CD3e molecule, epsilon (CD3 TCR complex) antibody CD3e molecule, epsilon (CD3-TCR complex) antibody CD3E_HUMAN antibody IMD18 antibody T cell antigen receptor complex epsilon subunit of T3 antibody T cell surface antigen T3/Leu 4 epsilon chain antibody T cell surface glycoprotein CD3 epsilon chain antibody T-cell surface antigen T3/Leu-4 epsilon chain antibody T-cell surface glycoprotein CD3 epsilon chain antibody T3E antibody TCRE antibody
Abbreviation: CD3E
Swiss Prot: P07766 Human
Cellular Locus: Cell membrane.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within human CD3 epsilon aa 153-203 (Cytoplasmic).
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IP, IF-Cell, IF-Tissue
Positive Control: Human thymus tissue lysate, Jurkat cell lysate, human tonsil tissue, human spleen tissue, Jurkat.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P:1:50-1:1;000 ;IF-Cell: 1:50-1:100 ;IF-Tissue: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 23 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for CD3 epsilon Recombinant Rabbit Monoclonal Antibody [SY0239]?

The catalog number for CD3 epsilon Recombinant Rabbit Monoclonal Antibody [SY0239] is ET1607-29.

What sizes are available for CD3 epsilon Recombinant Rabbit Monoclonal Antibody [SY0239]?

CD3 epsilon Recombinant Rabbit Monoclonal Antibody [SY0239] is available in the following size(s): 100 µL.

Is CD3 epsilon Recombinant Rabbit Monoclonal Antibody [SY0239] in stock?

CD3 epsilon Recombinant Rabbit Monoclonal Antibody [SY0239] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD3 epsilon Recombinant Rabbit Monoclonal Antibody [SY0239] used for?

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.