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Product details

PI 3 Kinase Class 3 Recombinant Rabbit Monoclonal Antibody [SY0286]

Catalog number ET1607-74

Price for ET1607-74

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Size / count 100 µL

About this product

Phosphatidylinositol 3-kinase catalytic subunit type 3 is an enzyme subunit that in humans is encoded by the PIK3C3 gene. It's a class III phosphoinositide 3-kinase. It is ubiquitously expressed with predominant expression in skeletal muscle and is believed to participate in endosome to lysosome transport, multivesicular body formation, autophagy and retrograde endosome to Golgi transport. PI 3-kinase p100 is the catalytic subunit of class III PI3Ks and forms a heterodimer with p150, a regulatory subunit of class 3 PI3Ks. PI 3-kinase p100 exclusively phosphorylates phosphatidylinositol to produce PtdIns3P. Unlike class I PI3Ks, whose activities are enhanced in the presence of magnesium, PI 3-kinase p100 activity is enhanced by manganese. Its activity can also be regulated by nutrients, suggesting an important role of PI-3 kinase p100 in the regulation of mTOR protein synthesis and autophagy.

Specifications

Catalog number
ET1607-74
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
hVps34 antibody MGC61518 antibody Phosphatidylinositol 3 kinase catalytic subunit type 3 antibody Phosphatidylinositol 3 kinase class 3 antibody Phosphatidylinositol 3 kinase p100 subunit antibody Phosphatidylinositol 3-kinase catalytic subunit type 3 antibody Phosphatidylinositol 3-kinase p100 subunit antibody Phosphoinositide 3 kinase class 3 antibody Phosphoinositide-3-kinase class 3 antibody PI3 kinase type 3 antibody PI3-kinase type 3 antibody PI3K type 3 antibody Pik3c3 antibody PK3C3_HUMAN antibody PtdIns 3 kinase type 3 antibody PtdIns-3-kinase type 3 antibody Vps 34 antibody Vps34 antibody
Abbreviation
PI3-kinase type 3, PI3K type 3, PtdIns-3-kinase type 3, PIK3C3
Swiss Prot
Q8NEB9 Human, Q6PF93 Mouse, O88763 Rat
Cellular Locus
Midbody, Late endosome, Cytoplasmic vesicle.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within human PI 3 Kinase Class 3 aa 830-870.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
IHC-P, FC
Positive Control
Human stomach cancer tissue, mouse brain tissue, rat brain tissue, A549.
Concentration
1 mg/mL
Dilution
IHC-P: 1:50-1:200 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 102 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for PI 3 Kinase Class 3 Recombinant Rabbit Monoclonal Antibody [SY0286]?

The catalog number for PI 3 Kinase Class 3 Recombinant Rabbit Monoclonal Antibody [SY0286] is ET1607-74.

What sizes are available for PI 3 Kinase Class 3 Recombinant Rabbit Monoclonal Antibody [SY0286]?

PI 3 Kinase Class 3 Recombinant Rabbit Monoclonal Antibody [SY0286] is available in the following size(s): 100 µL.

Is PI 3 Kinase Class 3 Recombinant Rabbit Monoclonal Antibody [SY0286] in stock?

PI 3 Kinase Class 3 Recombinant Rabbit Monoclonal Antibody [SY0286] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PI 3 Kinase Class 3 Recombinant Rabbit Monoclonal Antibody [SY0286] used for?

Phosphatidylinositol 3-kinase catalytic subunit type 3 is an enzyme subunit that in humans is encoded by the PIK3C3 gene. It's a class III phosphoinositide 3-kinase. It is ubiquitously expressed with predominant expression in skeletal muscle and is believed to participate in endosome to lysosome tra

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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