Phospho-IRF3 (S386) Recombinant Rabbit Monoclonal Antibody [SU03-28]

Catalog number ET1608-22

Price for ET1608-22

Size / count 100 µL

About this product

Interferon regulatory factor 3, also known as IRF3, is an interferon regulatory factor. IRF3 is a member of the interferon regulatory transcription factor (IRF) family. IRF3 was originally discovered as a homolog of IRF1 and IRF2. IRF3 has been further characterized and shown to contain several functional domains including a nuclear export signal, a DNA-binding domain, a C-terminal IRF association domain and several regulatory phosphorylation sites. IRF3 is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. The complex translocates into the nucleus for the transcriptional activation of interferons alpha and beta, and further interferon-induced genes.

Specifications

Catalog number: ET1608-22
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: IIAE7 antibody Interferon regulatory factor 3 antibody IRF 3 antibody IRF-3 antibody IRF3 antibody IRF3_HUMAN antibody MGC94729 antibody
Abbreviation: IRF-3, IRF3
Swiss Prot: Q14653 Human, P70671 Mouse
Cellular Locus: Cytoplasm, Nucleus, Mitochondrion.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Ser386 of human IRF3.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue
Positive Control: MCF7 treated with 100nM Calyculin A for 30 minutes whole cell lysate, NIH/3T3 treated with 100nM Calyculin A for 30 minutes cell lysate, MCF-7.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000 ;IF-Cell: 1:50-1:200 ;IF-Tissue: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 47 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Phospho-IRF3 (S386) Recombinant Rabbit Monoclonal Antibody [SU03-28]?

The catalog number for Phospho-IRF3 (S386) Recombinant Rabbit Monoclonal Antibody [SU03-28] is ET1608-22.

What sizes are available for Phospho-IRF3 (S386) Recombinant Rabbit Monoclonal Antibody [SU03-28]?

Phospho-IRF3 (S386) Recombinant Rabbit Monoclonal Antibody [SU03-28] is available in the following size(s): 100 µL.

Is Phospho-IRF3 (S386) Recombinant Rabbit Monoclonal Antibody [SU03-28] in stock?

Phospho-IRF3 (S386) Recombinant Rabbit Monoclonal Antibody [SU03-28] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-IRF3 (S386) Recombinant Rabbit Monoclonal Antibody [SU03-28] used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.