Cytokeratin 8 Recombinant Rabbit Monoclonal Antibody [SU0338] — image 1 of 3

Product details

Cytokeratin 8 Recombinant Rabbit Monoclonal Antibody [SU0338]

Catalog number ET1608-32

Discontinued

Price for ET1608-32

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Keratin, type II cytoskeletal 8 also known as cytokeratin-8 (CK-8) or keratin-8 (K8) is a keratin protein that is encoded in humans by the KRT8 gene. It is often paired with keratin 18. Antibodies to CK8 can be used to differentiate lobular carcinoma of the breast from ductal carcinoma of the breast. In normal tissue, it reacts mainly with secretory epithelia, but not with squamous epithelium, such as that found in the skin, cervix, and esophagus. However, it also reacts with a range of malignant cells, including those derived from secretory epithelia, but also some squamous carcinomata, such as spindle cell carcinoma. It is considered useful in identifying microscopic metastases of breast carcinoma in lymph nodes, and in distinguishing Paget's disease from malignant melanoma. It also reacts with neuroendocrine tumors. Keratin 8 is often used together with keratin 18 and keratin 19 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.

Specifications

Catalog number: ET1608-32
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9000-83-3
Product Name Alternative: CARD2 antibody Cell proliferation inducing gene 46 protein antibody Cell proliferation inducing protein 46 antibody CK 8 antibody CK-8 antibody CK8 antibody CYK8 antibody Cytokeratin 8 antibody Cytokeratin-8 antibody K2C8 antibody K2C8_HUMAN antibody K8 antibody Keratin 8 antibody Keratin antibody keratin type II cytoskeletal 8 antibody Keratin-8 antibody KRT8 antibody type II cytoskeletal 8 antibody Type-II keratin Kb8 antibody
Abbreviation: CK-8, K8, KRT8, CYK8
Swiss Prot: P05787 Human, P11679 Mouse
Cellular Locus: Nucleoplasm, Nucleus matrix, Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic peptide within Human Cytokeratin 8 aa 321-370 / 483.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Positive Control: Hela cell lysate, A431 cell lysate, Hela, MCF-7, A431, human liver tissue, human breast carcinoma tissue, human breast tissue, SK-Br-3, HepG2.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IF-Cell: 1:400-1:800 ;IF-Tissue: 1:400-1:800 ;IHC-P: 1:50-1:1,500 ;FC: 1:500-1:1,000 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 54 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Cytokeratin 8 Recombinant Rabbit Monoclonal Antibody [SU0338]?

The catalog number for Cytokeratin 8 Recombinant Rabbit Monoclonal Antibody [SU0338] is ET1608-32.

Is Cytokeratin 8 Recombinant Rabbit Monoclonal Antibody [SU0338] in stock?

Cytokeratin 8 Recombinant Rabbit Monoclonal Antibody [SU0338] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cytokeratin 8 Recombinant Rabbit Monoclonal Antibody [SU0338] used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.