Phospho-c-Jun (S63) Recombinant Rabbit Monoclonal Antibody [SY0297]

About this product

c-Jun is a protein that in humans is encoded by the JUN gene. c-Jun, in combination with c-Fos, forms the AP-1 early response transcription factor. It was first identified as the Fos-binding protein p39 and only later rediscovered as the product of the JUN gene. c-jun was the first oncogenic transcription factor discovered. The proto-oncogene c-Jun is the cellular homolog of the viral oncoprotein v-jun (P05411). The viral homolog v-jun was discovered in avian sarcoma virus 17 and was named for ju-nana, the Japanese word for 17. The human JUN encodes a protein that is highly similar to the viral protein, which interacts directly with specific target DNA sequences to regulate gene expression. This gene is intronless and is mapped to 1p32-p31, a chromosomal region involved in both translocations and deletions in human malignancies.

Specifications

Catalog number

ET1608-4

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Activator protein 1 antibody AP 1 antibody AP1 antibody cJun antibody Enhancer Binding Protein AP1 antibody Jun Activation Domain Binding Protein antibody JUN antibody Jun oncogene antibody JUN protein antibody Jun proto oncogene antibody JUN_HUMAN antibody JUNC antibody Oncogene JUN antibody p39 antibody Proto oncogene c jun antibody Proto oncogene cJun antibody Proto-oncogene c-jun antibody Transcription Factor AP 1 antibody Transcription factor AP-1 antibody Transcription Factor AP1 antibody V jun avian sarcoma virus 17 oncogene homolog antibody V jun sarcoma virus 17 oncogene homolog (avian) antibody V jun sarcoma virus 17 oncogene homolog antibody V-jun avian sarcoma virus 17 oncogene homolog antibody vJun Avian Sarcoma Virus 17 Oncogene Homolog antibody

Abbreviation

AP1, JUN

Swiss Prot

P05412 Human, P05627 Mouse, P17325 Rat

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic phospho-peptide corresponding to residues surrounding Ser63 of Human c-Jun aa 31-80 / 331.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

C6 treated with 25μg/mL Anisomycin for 30 minutes cell lysate, A549 treated with 250ng/mL anisomycin for 30 minutes whole cell lysate, NIH/3T3 treated with 250ng/mL anisomycin for 30 minutes whole cell lysate, PC-3M, MCF-7, A549, human breast carcinoma tissue, human tonsil tissue, human colon carcinoma tissue, human endometrial tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:50-1:500

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 36 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes