Calreticulin Recombinant Rabbit Monoclonal Antibody [SU37-03]

About this product

Calnexin and calregulin (also called calreticulin) are calcium-binding proteins that are localized to the endoplasmic reticulum, Calnexin to the membrane and calregulin to the lumen. Calnexin is a type I membrane protein that interacts with newly synthesized glycoproteins in the endoplasmic reticulum. It may play a role in assisting with protein assembly and in retaining unassembled protein subunits in the endoplasmic reticulum. Calregulin has both low- and high-affinity calcium-binding sites. Neither Calnexin nor calregulin contains the calcium-binding "E-F hand" motif found in calmodulins. Calnexin and calregulin are important for the maturation of glycoproteins in the endoplasmic reticulum and appear to bind many of the same proteins.

Specifications

Catalog number

ET1608-60

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

Yes

CAS Number

9000-83-3

Product Name Alternative

Autoantigen RO antibody CALR antibody CALR protein antibody CALR_HUMAN antibody Calregulin antibody Calreticulin antibody cC1qR antibody CRP55 antibody CRT antibody CRTC antibody Endoplasmic reticulum resident protein 60 antibody Epididymis secretory sperm binding protein Li 99n antibody ERp60 antibody FLJ26680 antibody grp60 antibody HACBP antibody HEL S 99n antibody RO antibody Sicca syndrome antigen A (autoantigen Ro; calreticulin) antibody Sicca syndrome antigen A antibody SSA antibody

Abbreviation

ERp60, CALR

Swiss Prot

P27797 Human, P14211 Mouse, P18418 Rat

Cellular Locus

Endoplasmic reticulum lumen, Cytoplasm, Secreted, Cell surface, Sarcoplasmic reticulum lumen, nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human Calreticulin aa 40-89 / 417.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC, IP

Positive Control

HepG2 cell lysate, HeLa cell lysate, HL-60 cell lysate, C2C12 cell lysate, C6 cell lysate, mouse liver tissue lysate, rat liver tissue lysate, Hela, NIH/3T3 cell lysate, NIH/3T3, human liver tissue, human liver carcinoma tissue, human kidney tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:5,000-1:50,000 ;IF-Cell: 1:2,000 ;IHC-P: 1:50 ;FC: 1:2,000 ;IP: Use at an assay dependent concentration.

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 48 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes