p16INK4a Recombinant Rabbit Monoclonal Antibody [SU0702] — image 1 of 3

Product details

p16INK4a Recombinant Rabbit Monoclonal Antibody [SU0702]

Catalog number ET1608-62

Discontinued

Price for ET1608-62

Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

p16 (also known as p16INK4a, cyclin-dependent kinase inhibitor 2A, CDKN2A, multiple tumor suppressor 1 and numerous other synonyms), is a protein that slows cell division by slowing the progression of the cell cycle from the G1 phase to the S phase, thereby acting as a tumor suppressor. It is encoded by the CDKN2A gene. A deletion (the omission of a part of the DNA sequence during replication) in this gene can result in insufficient or non-functional p16, accelerating the cell cycle and resulting in many types of cancer. p16 can be used as a biomarker to improve the histological diagnostic accuracy of grade 3 cervical intraepithelial neoplasia (CIN). p16 is also implicated in the prevention of melanoma, oropharyngeal squamous cell carcinoma, cervical cancer, vulvar cancer and esophageal cancer.

Specifications

Catalog number: ET1608-62
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: Yes
CAS Number: 9000-83-3
Product Name Alternative: CCM2 antibody CDK4 inhibitor p16 INK4 antibody CDK4I antibody CDKN2 antibody CDKN2A antibody Cell cycle negative regulator beta antibody CMM2 antibody Cyclin dependent kinase 4 inhibitor A antibody Cyclin dependent kinase inhibitor 2A (melanoma p16 inhibits CDK4) antibody Cyclin Dependent Kinase Inhibitor 2A antibody Cyclin dependent kinase inhibitor 2A isoform 4 antibody Cyclin dependent kinase inhibitor 2A isoforms 1/2/3 antibody Cyclin dependent kinase inhibitor p16 antibody INK4 antibody INK4A antibody MLM antibody MTS1 antibody Multiple tumor suppressor 1 antibody p14 antibody p16 antibody P16INK4 antibody p16INK4a antibody p19 antibody p19Arf antibody TP16 antibody
Abbreviation: CDK4I, MTS-1, p16-INK4, p16INK4A
Swiss Prot: P42771 Human
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human p16INK4a aa 107-156 / 156.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC, IP
Positive Control: 293 cell lysate, SiHa cell lysate, HepG2, Hela, PC-3M, human colon carcinoma tissue, human cervical carcinoma tissue, human ovary carcinoma tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:50-1:200 ;FC: 1:50-1:100 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 16 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for p16INK4a Recombinant Rabbit Monoclonal Antibody [SU0702]?

The catalog number for p16INK4a Recombinant Rabbit Monoclonal Antibody [SU0702] is ET1608-62.

Is p16INK4a Recombinant Rabbit Monoclonal Antibody [SU0702] in stock?

p16INK4a Recombinant Rabbit Monoclonal Antibody [SU0702] is currently made to order / not held in immediate stock. Contact us for lead time.

What is p16INK4a Recombinant Rabbit Monoclonal Antibody [SU0702] used for?

Can this product be used for co-immunoprecipitation (Co-IP)?

Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.

Is this kit compatible with automated liquid handling platforms?

Automation compatibility varies by kit and isn’t always listed on the datasheet. Contact our technical support team with details of your platform so we can confirm with the manufacturer.

What applications has this product been validated for?

Validated applications such as WB, ELISA, IHC, ICC, or FC are listed on the product datasheet. If you need application-specific validation data before ordering, contact our technical support team with the catalogue number.