mGluR5 Recombinant Rabbit Monoclonal Antibody [ST51-00] — image 1 of 3

Product details

mGluR5 Recombinant Rabbit Monoclonal Antibody [ST51-00]

Catalog number ET1609-36

Price for ET1609-36

Size / count 100 µL

About this product

The mGluR proteins (metabotropic Glutamate Receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic Glutamate Receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR1 and mGluR5 are mediated by a G protein that activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight sub-types of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-5, which can interact with SIAH-1, RyR-1, RyR-2, ITPR1, Shank 1, Shank 3 and GRASP, acts as a receptor for glutamate. The PPXXf motif of mGluR-5 binds to HOM1, HOM2 and HOM3.

Specifications

Catalog number: ET1609-36
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Glutamate receptor metabotropic 5 antibody GPRC1E antibody Grm5 antibody GRM5_HUMAN antibody Metabotropic glutamate receptor 5 antibody Metabotropic glutamate receptor 5 variant F antibody Metabotropic glutamate receptor 5 variant G antibody Metabotropic glutamate receptor 5 variant H antibody mGlu5 antibody mGluR5 antibody PPP1R86 antibody Protein phosphatase 1 regulatory subunit 86 antibody
Abbreviation: mGluR5, Grm5, Gprc1e, Mglur5
Swiss Prot: P41594 Human, Q3UVX5 Mouse, P31424 Rat
Cellular Locus: Cell membrane.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within Human mGluR5 aa 1,163-1,212 / 1,212.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Tissue, IHC-P, IP
Positive Control: Human brain tissue lysate, Mouse brain tissue lysate, Rat brain tissue lysate, human brain tissue, mouse brain tissue, rat brain tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IF-Tissue: 1:50-1:200 ;IHC-P: 1:200-1:1,000 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 132 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for mGluR5 Recombinant Rabbit Monoclonal Antibody [ST51-00]?

The catalog number for mGluR5 Recombinant Rabbit Monoclonal Antibody [ST51-00] is ET1609-36.

What sizes are available for mGluR5 Recombinant Rabbit Monoclonal Antibody [ST51-00]?

mGluR5 Recombinant Rabbit Monoclonal Antibody [ST51-00] is available in the following size(s): 100 µL.

Is mGluR5 Recombinant Rabbit Monoclonal Antibody [ST51-00] in stock?

mGluR5 Recombinant Rabbit Monoclonal Antibody [ST51-00] is currently made to order / not held in immediate stock. Contact us for lead time.

What is mGluR5 Recombinant Rabbit Monoclonal Antibody [ST51-00] used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.