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Product details

ROCK1 Recombinant Rabbit Monoclonal Antibody [ST05-19]

Catalog number ET1609-53

Price for ET1609-53

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Size / count 100 µL

About this product

Rho, the Ras-related small GTPase, is responsible for the regulation of Actin-based cytoskeletal structures including stress fibers, focal adhesions and the contractile ring apparatus. Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known about signaling downstream of Rho, a host of putative Rho effector proteins have been described, including rhophilin, Rhotekin, citron and the serine/threonine kinase, protein kinase N. Two additional Rho-activated serine/threonine kinases have been described, designated Rock-1 and Rock-2 (also referred to as Roka, for Rho-associated coil-containing protein kinase). Rock-1 and Rock-2 share a structural similarity with myotonic dystrophy kinase.

Specifications

Catalog number
ET1609-53
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
coiled-coil-containing protein kinase 1 antibody coiled-coil-containing protein kinase I antibody MGC131603 antibody MGC43611 antibody p160 Rhoassociated coiled coil-forming protein kinase antibody p160 ROCK-1 antibody p160 ROCK1 antibody p160ROCK antibody PRO0435 antibody Renal carcinoma antigen NY REN 35 antibody Renal carcinoma antigen NY-REN-35 antibody Rho associated coiled coil containing protein kinase 1 antibody Rho associated protein kinase 1 antibody Rho kinase antibody Rho-alpha kinase antibody Rho-associated antibody Rho-associated protein kinase 1 antibody ROCK I antibody ROCK-I antibody ROCK1 antibody ROCK1_HUMAN antibody Rok antibody rokalpha antibody
Abbreviation
ROCK-I, p160ROCK, ROCK1
Swiss Prot
Q13464 Human, P70335 Mouse, Q63644 Rat
Cellular Locus
Cell membrane, Cell projection, Cytoplasm, Cytoskeleton, Golgi apparatus, Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human ROCK1 aa aa 1104-1149 / 1,354.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Tissue, IHC-P, IP
Positive Control
A431 cell lysate, Human lung tissue lysate, Mouse spleen tissue lysate, C6 cell lysate, L6 cell lysate, human thyroid tissue, mouse thyroid tissue, rat thyroid tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:5,000 ;IF-Tissue: 1:50 ;IHC-P: 1:50-1:200 ;IP: Use at an assay dependent concentration.
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 158 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for ROCK1 Recombinant Rabbit Monoclonal Antibody [ST05-19]?

The catalog number for ROCK1 Recombinant Rabbit Monoclonal Antibody [ST05-19] is ET1609-53.

What sizes are available for ROCK1 Recombinant Rabbit Monoclonal Antibody [ST05-19]?

ROCK1 Recombinant Rabbit Monoclonal Antibody [ST05-19] is available in the following size(s): 100 µL.

Is ROCK1 Recombinant Rabbit Monoclonal Antibody [ST05-19] in stock?

ROCK1 Recombinant Rabbit Monoclonal Antibody [ST05-19] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ROCK1 Recombinant Rabbit Monoclonal Antibody [ST05-19] used for?

Rho, the Ras-related small GTPase, is responsible for the regulation of Actin-based cytoskeletal structures including stress fibers, focal adhesions and the contractile ring apparatus. Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known

What is the immunogen used to generate this antibody?

Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

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