Phospho-BTK (Y223) Recombinant Rabbit Monoclonal Antibody [ST51-05]

Catalog number ET1609-55

Price for ET1609-55

Size / count 100 µL

About this product

The Tec family of non-receptor tyrosine kinases is composed of six proteins designated Tec, Emt (also known as Itk or Tsk), Btk (previously known as Atk, BPK or Emb), Bmx, Txk (also known as Rlk) and Dsrc28C. All members of the family contain SH3 and SH2 domains and, with the exception of Txk and Dsrc28C, also contain a pleckstrin homology (PH) and a Tec homology (TH) domain in their amino termini. Four alternatively spliced forms of Tec are found to be expressed broadly in cells of hematopoietic lineage and hepatocytes. The Emt gene product associates with CD28 and becomes activated subsequent to CD28 ligation. Btk is necessary for proper B cell development, and mutations in the gene encoding Btk have been associated with families suffering from X-linked agammaglobulinemia, also referred to as Bruton’s disease. The Bmx protein shares a high degree of homology with Btk and seems to be expressed at highest levels in the heart. Txk expression is T cell-specific, while expression of the Drosophila Tec homolog, Dsrc28C, is developmentally regulated.

Specifications

Catalog number: ET1609-55
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Agammaglobulinaemia tyrosine kinase antibody AGMX 1 antibody AGMX1 antibody AT antibody ATK antibody B cell progenitor kinase antibody B-cell progenitor kinase antibody BPK antibody Bruton agammaglobulinemia tyrosine kinase antibody Bruton tyrosine kinase antibody Bruton’s Tyrosine Kinase antibody Btk antibody BTK_HUMAN antibody dominant-negative kinase-deficient Brutons tyrosine kinase antibody IMD 1 antibody IMD1 antibody MGC126261 antibody MGC126262 antibody OTTHUMP00000063593 antibody PSCTK 1 antibody PSCTK1 antibody truncated Bruton agammaglobulinemia tyrosine kinase antibody Tyrosine protein kinase BTK antibody Tyrosine-protein kinase BTK antibody tyrosine-protein kinase BTK isoform (lacking exon 14 antibody XLA antibody
Abbreviation: ATK, BPK, BTK, AGMX1, ATK, BPK
Swiss Prot: Q06187 Human, P35991 Mouse
Cellular Locus: Cytoplasm, Nucleus, Cell membrane.
Host: Rabbit
Species Reactivity: Human, Mouse
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Tyr223 of human BTK.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IP
Positive Control: K562 cells treated with pervanadate.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IP: Use at an assay dependent concentration.
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 76 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Phospho-BTK (Y223) Recombinant Rabbit Monoclonal Antibody [ST51-05]?

The catalog number for Phospho-BTK (Y223) Recombinant Rabbit Monoclonal Antibody [ST51-05] is ET1609-55.

What sizes are available for Phospho-BTK (Y223) Recombinant Rabbit Monoclonal Antibody [ST51-05]?

Phospho-BTK (Y223) Recombinant Rabbit Monoclonal Antibody [ST51-05] is available in the following size(s): 100 µL.

Is Phospho-BTK (Y223) Recombinant Rabbit Monoclonal Antibody [ST51-05] in stock?

Phospho-BTK (Y223) Recombinant Rabbit Monoclonal Antibody [ST51-05] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-BTK (Y223) Recombinant Rabbit Monoclonal Antibody [ST51-05] used for?

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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