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Product details

HIF-1 beta Recombinant Rabbit Monoclonal Antibody [ST05-25]

Catalog number ET1609-67

Price for ET1609-67

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Size / count 100 µL

About this product

AhR, Arnt 1, Arnt 2 and BMAL1 are members of a family of transcription factors that contain a basic helix-loop-helix motif and a common “PAS” motif. The aromatic (aryl) hydrocarbon receptor, AhR, is a ligand dependent transcription factor that interacts with specific DNA sequences termed xenobiotic responsive elements (XREs) to activate several genes including CYP1A1, glutathione S-transferase Ya subunit and DT-diaphorase. The Ah receptor nuclear translocator proteins (Arnt 1 or Arnt 2) are required for ligand-dependent nuclear translocation of the Ah receptor and are also necessary for Ah receptor binding to the XRE element. Arnt 2 (aryl hydrocarbon receptor nuclear translocator 2), also known as Hif-2b or bHLHe1, is a 712 amino acid nuclear protein that is exclusively expressed in adult brain and kidney. Containing a basic helix-loop-helix (bHLH) domain, a PAC (PAS-associated C-terminal) domain and two PAS (PER-ARNT-SIM) domains, Arnt 2 specifically recognizes the xenobiotic response element (XRE).

Specifications

Catalog number
ET1609-67
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
arnT antibody ARNT protein antibody ARNT_HUMAN antibody Aryl hydrocarbon receptor nuclear translocator antibody bHLHe2 antibody Class E basic helix-loop-helix protein 2 antibody Dioxin receptor antibody Dioxin receptor nuclear translocator antibody Drnt antibody HIF 1 beta antibody HIF 1beta antibody HIF-1-beta antibody HIF1-beta antibody HIF1B antibody HIF1beta antibody Hypoxia Inducible Factor 1 antibody Hypoxia inducible factor 1 beta antibody Hypoxia-inducible factor 1-beta antibody nuclear translocator antibody Tango antibody
Abbreviation
ARNT protein, bHLHe2, HIF-1-beta, HIF1-beta, ARNT, BHLHE2
Swiss Prot
P27540 Human
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human HIF-1 beta aa 479-789 / 789.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Human liver tissue lysates, human liver tissue, human fallopian tube tissue, human placenta tissue, human uterus tissue.
Concentration
1 mg/mL
Dilution
WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 87 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for HIF-1 beta Recombinant Rabbit Monoclonal Antibody [ST05-25]?

The catalog number for HIF-1 beta Recombinant Rabbit Monoclonal Antibody [ST05-25] is ET1609-67.

What sizes are available for HIF-1 beta Recombinant Rabbit Monoclonal Antibody [ST05-25]?

HIF-1 beta Recombinant Rabbit Monoclonal Antibody [ST05-25] is available in the following size(s): 100 µL.

Is HIF-1 beta Recombinant Rabbit Monoclonal Antibody [ST05-25] in stock?

HIF-1 beta Recombinant Rabbit Monoclonal Antibody [ST05-25] is currently made to order / not held in immediate stock. Contact us for lead time.

What is HIF-1 beta Recombinant Rabbit Monoclonal Antibody [ST05-25] used for?

AhR, Arnt 1, Arnt 2 and BMAL1 are members of a family of transcription factors that contain a basic helix-loop-helix motif and a common “PAS” motif. The aromatic (aryl) hydrocarbon receptor, AhR, is a ligand dependent transcription factor that interacts with specific DNA sequences termed xenobiotic

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

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