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Product details

Tuberin Recombinant Rabbit Monoclonal Antibody [SC05-59]

Catalog number ET1610-10

Price for ET1610-10

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Size / count 100 µL

About this product

Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes a protein called tuberin and the other loci, tuberous sclerosis-1 gene (TSC1), encodes a protein called hamartin. Tuberin and hamartin interact with each other forming a cystoplasmic complex. Hamartin interacts with the ezrin-radixin-moesin (ERM) family of actin-binding proteins and inhibition of hamartin activity results in loss of cell adhesion. Hamartin is present in most adult tissues with strong expression in brain, heart, and kidney.

Specifications

Catalog number
ET1610-10
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
FLJ43106 antibody LAM antibody OTTHUMP00000158940 antibody OTTHUMP00000198394 antibody OTTHUMP00000198395 antibody PPP1R160 antibody Protein phosphatase 1, regulatory subunit 160 antibody tsc2 antibody TSC2_HUMAN antibody TSC4 antibody TSC4 gene, formerly antibody TSC4, formerly antibody Tuberin antibody Tuberous sclerosis 2 antibody Tuberous sclerosis 2 protein antibody Tuberous sclerosis 2 protein homolog antibody
Abbreviation
TSC2, TSC4
Swiss Prot
P49815 Human, Q61037 Mouse, P49816 Rat
Cellular Locus
Cytoplasm, Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Tuberin aa 1760-1807 / 1807.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
HEK-293 cell lysate, HeLa cell lysate, LNCaP cell lysate, C6 cell lysate, Mouse brain tissue lysate, Rat brain tissue lysate, human testis tissue, mouse testis tissue, rat testis tissue, HeLa.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:200 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
201 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Tuberin Recombinant Rabbit Monoclonal Antibody [SC05-59]?

The catalog number for Tuberin Recombinant Rabbit Monoclonal Antibody [SC05-59] is ET1610-10.

What sizes are available for Tuberin Recombinant Rabbit Monoclonal Antibody [SC05-59]?

Tuberin Recombinant Rabbit Monoclonal Antibody [SC05-59] is available in the following size(s): 100 µL.

Is Tuberin Recombinant Rabbit Monoclonal Antibody [SC05-59] in stock?

Tuberin Recombinant Rabbit Monoclonal Antibody [SC05-59] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Tuberin Recombinant Rabbit Monoclonal Antibody [SC05-59] used for?

Tuberous sclerosis complex (TSC) is an autosomal dominant genetic disorder characterized by mental retardation and the widespread development of distinctive tumors termed hamartomas. Two different genetic loci have been linked to TSC; one of these loci, the tuberous sclerosis-2 gene (TSC2), encodes

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

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