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Product details

Integrin alpha V Recombinant Rabbit Monoclonal Antibody [SC56-07]

Catalog number ET1610-15

Discontinued

Price for ET1610-15

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Size / count 100 µL

This variant is discontinued and cannot be added to your cart.

About this product

Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen and vitronectin. Certain integrins can also bind to soluble ligands, such as fibrinogen, or to counterreceptors on adjacent cells such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster integrins by binding to adjacent integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of integrin-mediated responses. In addition to mediating cell adhesion and cytoskeletal organization, integrins function as signaling receptors. Signals transduced by integrins play a role in many biological processes, including cell growth, differentiation, migration and apoptosis.

Specifications

Catalog number
ET1610-15
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9000-83-3
Product Name Alternative
CD51 antibody Integrin alpha-V light chain antibody integrin, alpha V (vitronectin receptor, alpha polypeptide, antigen CD51) antibody Integrin, alpha V antibody Integrin, beta 6 antibody ITAV_HUMAN antibody ITGAV antibody ITGB6 antibody Vitronectin receptor subunit alpha antibody
Abbreviation
ITGAV, MSK8, VNRA, ITGB6
Swiss Prot
P06756 Human, P43406 Mouse,
Cellular Locus
Membrane.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within of Human Integrin alpha V aa 1000-1048 / 1048.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, FC, IHC-P
Positive Control
A549 cell lysate, HeLa cell lysate, NIH/3T3 cell lysate, C6 cell lysate, rat heart tissue lysate, A549, SiHa, MCF-7, human placenta tissue.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:5,000 ;IF-Cell: 1:50-1:100 ;FC: 1:50-1:100 ;IHC-P: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 116 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Integrin alpha V Recombinant Rabbit Monoclonal Antibody [SC56-07]?

The catalog number for Integrin alpha V Recombinant Rabbit Monoclonal Antibody [SC56-07] is ET1610-15.

Is Integrin alpha V Recombinant Rabbit Monoclonal Antibody [SC56-07] in stock?

Integrin alpha V Recombinant Rabbit Monoclonal Antibody [SC56-07] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Integrin alpha V Recombinant Rabbit Monoclonal Antibody [SC56-07] used for?

Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than 20 different receptors. Most integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, collagen

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

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