PBP Recombinant Rabbit Monoclonal Antibody [SC58-09]

About this product

Members of the a-chemokine subfamily of inducible, secreted, pro-inflammatory cytokines contain a similar motif, in which the first two cysteine residues are separated by a single residue (Cys-X-Cys), and are also chemotactic for neutrophils. The platelet basic protein (PBP), a member of the a (lpha)-chemokine family, resides in the a (lpha)-granules of platelets and is released upon their activation. Proteolytic cleavage of the amino terminus of PBP leads to the generation of several peptides, which include mature PBP, connective tissue-activating peptide III (CTAP III, also designated low affinity platelet factor IV (LA-PF4)), b-thromboglobulin (b-TG), and neutrophil-activating peptide 2 (NAP-2). PBP and its N-truncated derivatives mediate inflammation and wound healing. Specifically, NAP-2 activates chemotaxis and degranulation in neutrophils during inflammation. The gene encoding human PBP maps to chromosome 4q12-q13.

Specifications

Catalog number

ET1610-18

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Epididymis luminal protein 210 antibody Epididymis secretory protein Li 34 antibody Epididymis secretory protein Li 96 antibody HCNP antibody HCNPpp antibody HEL 210 antibody HEL S 34 antibody HEL S 96 antibody Hippocampal cholinergic neurostimulating peptide antibody Neuropolypeptide h3 antibody PBP antibody PEBP antibody PEBP 1 antibody PEBP-1 antibody Pebp1 antibody PEBP1_HUMAN antibody Phosphatidylethanolamine binding protein antibody Phosphatidylethanolamine binding protein 1 antibody Prostatic binding protein antibody Prostatic-binding protein antibody R kip antibody Raf kinase inhibitor protein antibody Raf kinase inhibitory protein antibody RKIP antibody

Abbreviation

PEBP-1, RKIP, HCNP

Swiss Prot

P30086 Human, P70296 Mouse, P31044 Rat

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat, Zebrafish

Immunogen

Synthetic peptide within Human PBP aa 53-96 / 187.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IF-Tissue, IHC-P, IP

Positive Control

Mouse brain tissue lysate, SiHa cell lysate, mouse cerebellum tissue lysate, PC-3M, human kidney tissue, mouse brain tissue, mouse kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:1,000-1:5,000;IF-Cell: 1:50-1:200;IF-Tissue: 1:50-1:200;IHC-P: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

21 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes