BCL2A1 Recombinant Rabbit Monoclonal Antibody [SC05-42]

About this product

The Bcl-2 family of proteins is characterized by its ability to modulate cell death under a broad range of physiological conditions. Bcl-2 and Bcl-xL function to inhibit apoptosis while other members of the Bcl-2 family, Bax, Bad, Bak and Bcl-xS, oppose death-suppressing effects. An additional member of the family, A1 (also designated Bfl-1), dimerizes with both Bcl-2 and Bax and has been identified as a hematopoietic- specific, early inducible gene. While A1 demonstrates life promoting properties similar to those of Bcl-2, its function may be more temporally regulated during myeloid differentiation and dependent on additional growth stimuli to confer its life promoting properties. A1 is abundantly expressed in bone marrow and at low levels in other tissues. There is evidence that a correlation exists between a high expression of the A1 gene product and stomach cancer.

Specifications

Catalog number

ET1610-20

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

ACC 1 antibody ACC 2 antibody B2LA1_HUMAN antibody Bcl 2 related protein A1 antibody Bcl-2-like protein 5 antibody Bcl-2-related protein A1 antibody BCL2 related protein A1 antibody Bcl2-L-5 antibody BCL2A1 antibody BCL2L5 antibody BFL1 antibody GRS antibody HBPA1 antibody Hematopoietic BCL2 related protein A1 antibody Hemopoietic specific early response protein antibody Hemopoietic-specific early response protein antibody Protein BFL 1 antibody Protein BFL-1 antibody Protein GRS antibody

Abbreviation

Bcl2-L-5, BCL2A1

Swiss Prot

Q16548 Human, Q07440 Mouse

Cellular Locus

Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within Human BCL2A1 aa 2-48 / 175.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, FC

Positive Control

Human tonsil tissue, human kidney tissue, mouse liver tissue, mouse kidney tissue, 293, human liver tissue, human kidney tissue lysates.

Concentration

1 mg/mL

Dilution

WB: 1:1,000 ;IHC-P:1:50-1:400 ;FC: 1:50-1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 20 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Recombinant Antibody

Yes