Aurora B Recombinant Rabbit Monoclonal Antibody [SC55-08] — image 1 of 3

Product details

Aurora B Recombinant Rabbit Monoclonal Antibody [SC55-08]

Catalog number ET1610-25

Price for ET1610-25

Size / count 100 µL

About this product

Aurora related kinase-1 (ARK-1, STK15, Aurora2, Aik1) and -2 (ARK-2, STK12, Aurora1) are centrosome-associated serine/ threonine kinases that regulate centrosome separation, bipolar spindle assembly, and chromosome segregation during mitosis. ARK-1 and -2 are expressed in the nucleus and localize to distinct portions of mitotic machinery such as the centrosome, spindle poles (ARK-1), and midbody (ARK-2) during mitosis. ARK-1 and -2 transcripts are present at high levels in human thymus and fetal liver. ARK-1 protein has elevated expression in colon carcinoma lines (HT-29, SNU-C2B, COLO 205, SW480, 837 and 948) and accumulates during metaphase in HeLa cells. ARK-2 protein levels are maximal during both S and G2/M phases, whereas ARK-1 protein is degraded after G2/M via the ubiquitin-proteasome pathway. ARK-2 has a unique genetic loci relative to ARK-1, suggesting that these two kinases, with oncogenic potential, have different roles in cell cycle progression.

Specifications

Catalog number: ET1610-25
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: AIK2 antibody AIM-1 antibody AIM1 antibody ARK-2 antibody ARK2 antibody AurB antibody AURKB antibody AURKB_HUMAN antibody Aurora 1 antibody Aurora and Ipl1 like midbody associated protein 1 antibody Aurora kinase B antibody Aurora related kinase 2 antibody Aurora- and Ipl1-like midbody-associated protein 1 antibody Aurora-B antibody Aurora-related kinase 2 antibody Aurora/IPL1 related kinase 2 antibody Aurora/IPL1-related kinase 2 antibody IPL1 antibody PPP1R48 antibody Protein phosphatase 1 regulatory subunit 48 antibody Serine/theronine kinase 12 antibody Serine/threonine protein kinase 12 antibody Serine/threonine-protein kinase 12 antibody Serine/threonine-protein kinase aurora-B antibody STK-1 antibody STK1 antibody STK12 antibody STK5 antibody
Abbreviation: AIM-1, ARK-2, Aurora-related kinase 2, AURKB
Swiss Prot: Q96GD4 Human, O70126 Mouse, O55099 Rat
Cellular Locus: Nucleus, Cytoplasm, Chromosome.
Host: Rabbit
Species Reactivity: Human
Immunogen: Synthetic peptide within Human Aurora B aa 1-50 / 344.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P, IP, IF-Cell
Positive Control: Hela cell lysate, MCF-7 cell lysate, human tonsil tissue, HeLa.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:2,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:100
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 39 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Aurora B Recombinant Rabbit Monoclonal Antibody [SC55-08]?

The catalog number for Aurora B Recombinant Rabbit Monoclonal Antibody [SC55-08] is ET1610-25.

What sizes are available for Aurora B Recombinant Rabbit Monoclonal Antibody [SC55-08]?

Aurora B Recombinant Rabbit Monoclonal Antibody [SC55-08] is available in the following size(s): 100 µL.

Is Aurora B Recombinant Rabbit Monoclonal Antibody [SC55-08] in stock?

Aurora B Recombinant Rabbit Monoclonal Antibody [SC55-08] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Aurora B Recombinant Rabbit Monoclonal Antibody [SC55-08] used for?

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.