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Product details

Islet 1 Recombinant Rabbit Monoclonal Antibody [SC05-64]

Catalog number ET1610-33

Price for ET1610-33

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Size / count 100 µL

About this product

Islet-1 (ISL1 transcription factor, LIM/homeodomain) and Islet-2 (ISL2 transcription factor, LIM/homeodomain) contain amino-terminal LIM domains and a carboxy-terminal homeodomain and both influence developmental events. Islet-1 influences embryogenesis of the pancreatic islets of Langerhans and neural tube motor neuron differentiation. In developing mouse teeth, Islet-1 mediates patterning of dentition as an activator of Bmp4 expression in incisor (distal) areas of the stomatodeal epithelium. Islet-1 expression defines cardiac progenitor cell populations and is required for normal cardiac development and asymmetry. Islet-2 activity in newly generated motor neurons permits the diversification of visceral and somatic motor neuron subtypes in the developing spinal cord. Murine Islet-2 specifies retinal ganglion cell (RGC) laterality by repressing an ipsilateral pathfinding program unique to the ventral-temporal crescent (VTC) of RGCs in a Zic2- and EphB1-dependent manner.

Specifications

Catalog number
ET1610-33
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
Insulin gene enhancer protein ISL 1 antibody Insulin gene enhancer protein ISL-1 antibody Insulin related protein antibody ISL 1 antibody ISL LIM homeobox 1 antibody ISL1 antibody ISL1 transcription factor LIM homeodomain antibody ISL1 transcription factor, LIM/homeodomain (islet 1) antibody ISL1 transcription factor, LIM/homeodomain antibody ISL1_HUMAN antibody Islet-1 antibody Islet1 antibody
Abbreviation
Islet-1, ISL1
Swiss Prot
P61371 Human, P61372 Mouse, P61374 Rat
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human, Mouse, Rat
Immunogen
Synthetic peptide within Human Islet 1 aa 262-205 / 349.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC, IP, IHC-Fr
Positive Control
SH-SY5Y cell lysate, Neuro-2a cell lysate, PC-12 cell lysate, SH-SY5Y, Neuro-2a, human pancreas tissue, mouse embryo tissue, rat pancreas tissue.
Concentration
1 mg/mL
Dilution
WB: 1:2,000 ;IF-Cell: 1:100 ;IHC-P: 1:1,000 ;FC: 1:1,000 ;IP: 1-2μg/sample ;IHC-Fr: 1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 39 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Islet 1 Recombinant Rabbit Monoclonal Antibody [SC05-64]?

The catalog number for Islet 1 Recombinant Rabbit Monoclonal Antibody [SC05-64] is ET1610-33.

What sizes are available for Islet 1 Recombinant Rabbit Monoclonal Antibody [SC05-64]?

Islet 1 Recombinant Rabbit Monoclonal Antibody [SC05-64] is available in the following size(s): 100 µL.

Is Islet 1 Recombinant Rabbit Monoclonal Antibody [SC05-64] in stock?

Islet 1 Recombinant Rabbit Monoclonal Antibody [SC05-64] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Islet 1 Recombinant Rabbit Monoclonal Antibody [SC05-64] used for?

Islet-1 (ISL1 transcription factor, LIM/homeodomain) and Islet-2 (ISL2 transcription factor, LIM/homeodomain) contain amino-terminal LIM domains and a carboxy-terminal homeodomain and both influence developmental events. Islet-1 influences embryogenesis of the pancreatic islets of Langerhans and neu

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

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