Phospho-FAK (Y397) Recombinant Rabbit Monoclonal Antibody [SC54-07] — image 1 of 3

Product details

Phospho-FAK (Y397) Recombinant Rabbit Monoclonal Antibody [SC54-07]

Catalog number ET1610-34

Price for ET1610-34

Size / count 100 µL

About this product

Activation of integrins in the extracellular matrix (ECM) of eukaryotic cells promotes the formation of membrane adhesion complexes, known as focal adhesions, which can include cytoskeletal proteins and protein tyrosine kinases, such as focal adhesion kinase (FAK). Phosphorylation events occurring within focal adhesions influence numerous processes that include mitogenic signaling, cell survival, and cell motility. FAK is a non-receptor tyrosine kinase that is ubiquitously expressed and highly conserved between species. FAK is recruited by Integrin clusters and variably phosphorylated depending on the effector molecules present in the focal adhesion. Phosphorylation of FAK Tyr 397 decreases during serum starvation, contact inhibition, and cell cycle arrest, all conditions under which activating FAK Tyr 407 phosphorylation increases.

Specifications

Catalog number: ET1610-34
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: FADK 1 antibody FADK antibody FAK related non kinase polypeptide antibody FAK1 antibody FAK1_HUMAN antibody Focal adhesion kinase 1 antibody Focal adhesion Kinase antibody Focal adhesion kinase isoform FAK Del33 antibody Focal adhesion kinase related nonkinase antibody FRNK antibody p125FAK antibody pp125FAK antibody PPP1R71 antibody Protein phosphatase 1 regulatory subunit 71 antibody Protein tyrosine kinase 2 antibody Protein-tyrosine kinase 2 antibody Ptk2 antibody PTK2 protein tyrosine kinase 2 antibody
Abbreviation: FADK 1, FRNK, PPP1R71, PTK2
Swiss Prot: Q05397 Human, P34152 Mouse, O35346 Rat
Cellular Locus: Cytoplasm, Nucleus, Cell membrane, Cell junction.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic phospho-peptide corresponding to residues surrounding Tyr397 of human FAK.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P
Positive Control: Hela cell lysate, PC-3 cell lysate, Hela, N2A, NIH/3T3, mouse spleen tissue, rat spleen tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:1,000 ;IF-Cell: 1:50-1:100 ;IF-Tissue: 1:50-1:100 ;IHC-P: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 119 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Phospho-FAK (Y397) Recombinant Rabbit Monoclonal Antibody [SC54-07]?

The catalog number for Phospho-FAK (Y397) Recombinant Rabbit Monoclonal Antibody [SC54-07] is ET1610-34.

What sizes are available for Phospho-FAK (Y397) Recombinant Rabbit Monoclonal Antibody [SC54-07]?

Phospho-FAK (Y397) Recombinant Rabbit Monoclonal Antibody [SC54-07] is available in the following size(s): 100 µL.

Is Phospho-FAK (Y397) Recombinant Rabbit Monoclonal Antibody [SC54-07] in stock?

Phospho-FAK (Y397) Recombinant Rabbit Monoclonal Antibody [SC54-07] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Phospho-FAK (Y397) Recombinant Rabbit Monoclonal Antibody [SC54-07] used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.