- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
![PI3-kinase p110 subunit beta Recombinant Rabbit Monoclonal Antibody [SC0580] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea815b4/imageurl/et1610-36.webp)
Product details
Catalog number ET1610-36
Price for ET1610-36
Size / count 100 µL
Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. p110 expression is restricted to white blood cells. It has been shown to bind p85α and β, but it apparently does not phosphorylate these subunits. p110δ seems to have the capacity to autophosphorylate. p110γ does not interact with the p85 subunits. It has been shown to be activated by α and β γ heterotrimeric G proteins.
The catalog number for PI3-kinase p110 subunit beta Recombinant Rabbit Monoclonal Antibody [SC0580] is ET1610-36.
PI3-kinase p110 subunit beta Recombinant Rabbit Monoclonal Antibody [SC0580] is available in the following size(s): 100 µL.
PI3-kinase p110 subunit beta Recombinant Rabbit Monoclonal Antibody [SC0580] is currently made to order / not held in immediate stock. Contact us for lead time.
Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110
A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.
Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.
Suitability for Co-IP depends on the specific antibody and is noted under validated applications on the datasheet. If it isn’t listed, contact our technical support team for guidance based on your target and sample type.
