Cytokeratin 14 Recombinant Rabbit Monoclonal Antibody [SC65-06] — image 1 of 3

Product details

Cytokeratin 14 Recombinant Rabbit Monoclonal Antibody [SC65-06]

Catalog number ET1610-42

Price for ET1610-42

Size / count 100 µL

About this product

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed in pairs in both keratinized and non-keratinized epithelial tissue, where they constitute up to 85% of mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. The a-helical coiled-coil dimers associate laterally end-to-end to form 10 nm diameter filaments. Cytokeratins are useful markers of tissue differentiation and, in addition, they aid in the characterization of malignant tumors. In Bowen’s disease, the characteristic malignancy of the epidermis exhibits distinct expression patterns of Cytokeratin 14. The gene encoding human Cytokeratin 14 maps to chromosome 17q12-21. Mutations in this gene lead to epidermolysis bullosa simplex, an inheritied skin disorder characterized by skin blistering due to basal keratinocyte fragility.

Specifications

Catalog number: ET1610-42
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CK 14 antibody CK-14 antibody ck14 antibody Cytokeratin 14 antibody Cytokeratin-14 antibody Cytokeratin14 antibody Dowling Meara antibody EBS3 antibody EBS4 antibody Epidermolysis bullosa simplex antibody K14 antibody K1C14_HUMAN antibody Keratin 14 (epidermolysis bullosa simplex, Dowling-Meara, Koebner) antibody Keratin 14 antibody Keratin antibody Keratin type I cytoskeletal 14 antibody Keratin, type I cytoskeletal 14 antibody Keratin-14 antibody Keratin14 antibody Koebner antibody Krt 14 antibody Krt14 antibody NFJ antibody OTTHUMP00000164624 antibody type I cytoskeletal 14 antibody
Abbreviation: CK-14, K14, KRT14
Swiss Prot: P02533 Human, Q61781 Mouse, Q6IFV1 Rat
Cellular Locus: Cytoplasm, Nucleus.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Mouse Cytokeratin 14 aa 250-484 / 484.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IF-Tissue, IHC-P, FC
Positive Control: A431 cell lysate, mouse skin tissue lysate, B16F1, SW480, HepG2, human cervical carcinoma tissue, human skin tissue, rat skin tissue, mouse skin tissue, mouse prostate tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:2,000 ;IF-Cell: 1:100-1:500 ;IF-Tissue: 1:100-1:500 ;IHC-P: 1:100-1:1,500 ;FC: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 51 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Cytokeratin 14 Recombinant Rabbit Monoclonal Antibody [SC65-06]?

The catalog number for Cytokeratin 14 Recombinant Rabbit Monoclonal Antibody [SC65-06] is ET1610-42.

What sizes are available for Cytokeratin 14 Recombinant Rabbit Monoclonal Antibody [SC65-06]?

Cytokeratin 14 Recombinant Rabbit Monoclonal Antibody [SC65-06] is available in the following size(s): 100 µL.

Is Cytokeratin 14 Recombinant Rabbit Monoclonal Antibody [SC65-06] in stock?

Cytokeratin 14 Recombinant Rabbit Monoclonal Antibody [SC65-06] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cytokeratin 14 Recombinant Rabbit Monoclonal Antibody [SC65-06] used for?

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.